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US 11,445,952 B2Granted
Sensor systems, devices, and methods for continuous glucose monitoring
AssigneeMedtronic MiniMed, Inc.
InventorsKeith Nogueira, Taly G. Engel, Xiaolong Li, Bradley C. Liang, Rajiv Shah, Mike C. Liu, Andy Y. Tsai
Life of this patent
Estimating the term…
Abstract
Electrochemical impedance spectroscopy (EIS) may be used in conjunction with continuous glucose monitoring (CGM) to enable identification of valid and reliable sensor data, as well implementation of Smart Calibration algorithms.
Claims20
A method for real-time calibration of a glucose sensor for measuring a level of glucose in a body of a user, the glucose sensor including physical sensor electronics, a microcontroller, and a working electrode, the method comprising:
- (a) measuring, by the physical sensor electronics, an electrode current (Isig) for the working electrode;
- (b) obtaining a blood glucose (BG) value for the user;
- (c) performing, by the microcontroller, an electrochemical impedance spectroscopy (EIS) procedure for the working electrode to obtain a respective plurality of values of an impedance-based parameter for the working electrode, and expecting calibration errors based on the respective plurality of values of an impedance-based parameter;
- (d) providing, by the microcontroller, variable calibration error thresholds based on expectation of calibration error;
- (e) updating, by the microcontroller, a calibration factor CF with accepted BG values based on the variable calibration error thresholds;
- (f) calculating, by the microcontroller, a calibrated sensor glucose (SG) value associated with the Isig based on the updated CF and accepted BG values;
- (g) calculating, by the microcontroller, an amount of insulin to be delivered to the user based on the calibrated SG value;
- and
- (h) delivering the calculated amount of insulin to the user.
6 more elements
A method for operating a glucose sensor, the method comprising:
- measuring an electrode current (Isig) for a working electrode of the glucose sensor;
- performing an electrochemical impedance spectroscopy (EIS) procedure for the working electrode to obtain a respective plurality of values of an impedance-based parameter for the working electrode, and expecting calibration errors based on the respective plurality of values of an impedance-based parameter;
- updating a calibration factor CF with accepted BG values based on variable calibration error thresholds;
- calculating a calibrated sensor glucose (SG) value associated with the Isig based on the updated CF;
- calculating an amount of insulin to be delivered to the user based on the calibrated SG value;
- and
- delivering the calculated amount of insulin to the user.
4 more elements
Dependencies are inferred from the claim text.