Fermentation efficiency using yeast containing prions
AssigneePOET Research, Inc.
InventorsMalgorzata Maria Slupska, Stephen M. Lewis
Life of this patent
Estimating the term…
Abstract
Genetically modified microorganisms useful in fermentation and methods of using such microorganisms are provided. Such microorganisms contain a [GAR+] prion or are modified to contain a [GAR+] prion. Exemplary microorganisms include yeast such as S. cerevisiae. The microorganisms can be further modified to convert xylose and/or arabinose. Methods of fermentation using such microorganisms exhibit improved fermentation efficiency and improved microorganism viability.
Claims20
A method of producing ethanol from a multi-sugar feedstock having a blend of 5-carbon sugars and 6-carbon sugars, the method comprising inoculating the multi-sugar feedstock with [GAR+] Saccharomyces cerevisiae strain, which contains a C5 sugar metabolic pathway to ferment xylose and/or arabinose, and fermenting the feedstock, wherein:
- the [GAR+] Saccharomyces cerevisiae strain utilizes 5-carbon and 6-carbon sugars simultaneously during fermentation of the multi-sugar feedstock and ethanol is produced from the feedstock.
A method of producing ethanol from a multi-sugar feedstock having a blend of 5-carbon sugars and 6-carbon sugars, the method comprising inoculating the multi-sugar feedstock with a [GAR+] Saccharomyces cerevisiae strain, which contains a C5 sugar metabolic pathway to ferment xylose and/or arabinose, and fermenting the feedstock, wherein:
- the [GAR+] Saccharomyces cerevisiae strain utilizes the two or more sugars simultaneously during fermentation of the multi-sugar feedstock, ethanol is produced from the feedstock, and efficiency of conversion of non-glucose C6 sugars is improved relative to fermentation using [GAR−] yeast.
A method of producing ethanol from a multi-sugar feedstock having a blend of 5-carbon sugars and 6-carbon sugars, the method comprising inoculating the multi-sugar feedstock with a [GAR+] Saccharomyces cerevisiae strain, genetically modified to use xylose and/or arabinose, and fermenting the feedstock, wherein:
- the [GAR+] Saccharomyces cerevisiae strain utilizes the two or more sugars simultaneously during fermentation of the multi-sugar feedstock and ethanol is produced from the feedstock.
Dependencies are inferred from the claim text.