# US 11,439,753 B2 · Apparatus for regulating the concentration of glucose in the blood of a person

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- Number: US 11,439,753 B2
- Document ID: US11439753B2
- Status: Granted
- Kind: B2
- Application number: 16/464,883
- Filed: 2017-11-29
- Published: 2020-03-26
- Granted: 2022-09-13
- Earliest claimed: 2016-11-30
- Assignees: Inreda Diabetic B.V.
- Applicants: Inreda Diabetic B.V.
- Inventors: Robin Koops; Gijs Benno Westen
- Web page: https://patentgrep.com/patent/US11439753B2

## CPC

- A61B 5/14532: {for measuring glucose, e.g. by tissue impedance measurement}
- A61M 5/1723: {using feedback of body parameters, e.g. blood sugar or pressure}
- A61M 5/16836: {by sensing tissue properties at the infusion site, e.g. for detecting infiltration}
- A61M 39/0247: {Transcutaneous or percutaneous access sites to the inside of the body}
- A61B 5/01: Measuring temperature of body parts {; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue} (clinical contact thermometers G01K13/20)
- A61B 5/02: Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B 5/1112: {Global tracking of patients, e.g. by using GPS}
- A61B 5/4809: {Sleep detection, i.e. determining whether a subject is asleep or not}
- A61B 5/486: {Biofeedback (using electroencephalography [EEG] A61B5/375)}
- A61B 2562/0219: Inertial sensors, e.g. accelerometers, gyroscopes, tilt switches
- A61M 2205/18: with alarm
- A61M 2205/3303: Using a biosensor
- A61M 2205/3324: PH measuring means
- A61M 2205/3365: Rotational speed
- A61M 2205/3368: Temperature
- A61M 2230/06: Heartbeat rate only
- A61M 2230/201: Glucose concentration
- A61M 2230/208: pH-value
- A61M 2230/50: Temperature
- A61M 2230/63: Motion, e.g. physical activity
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

An apparatus for regulating the concentration of glucose in the blood of a person includes: at least one glucose sensor that is arranged to measure the glucose concentration of the person, for example in the interstitial fluid or blood; a pump for selectively introducing at least one substance influencing the blood glucose levels into the body of the person, for instance by at least one cannula or catheter to be inserted into the body of said person, and a control for controlling said at least one substance influencing the blood glucose levels to be introduced to the person based on data received from said glucose sensor. Said apparatus includes at least one further sensor that is arranged to monitor a further characteristic of the person. The at least one further sensor may include an accelerometer, a heart rate sensor, a temperature sensor, a pH sensor, a ketone sensor, a GPS receiver, and/or a skin resistance sensor.

## Claims

### Claim 1

An apparatus for regulating the concentration of glucose in the blood of a person, comprising:
at least one glucose sensor that is arranged to measure the glucose concentration of the person;
a pump for selectively introducing at least one substance influencing the blood glucose levels into the body of the person, and
a control for controlling said at least one substance influencing the blood glucose levels to be introduced to the person based on data received from said glucose sensor,
wherein said apparatus comprises at least one further sensor that is arranged to monitor a further characteristic of the person, wherein the at least one further sensor monitors the further characteristic of the person by means other than a video image of the person,
wherein said apparatus is arranged to determine, from the at least one further sensor, if said person is asleep or awake, and
when said apparatus determines that said person is asleep, said apparatus is arranged to:
temporarily reduce a volume of an alarm function of the apparatus; and/or
temporarily not provide an alarm; and/or
temporarily dim a display of the apparatus; and/or
temporarily not show messages of low priority; and/or
check and, if necessary, adapt settings of the apparatus.

### Claim 2 (depends on 1)

The apparatus according to claim 1, wherein said at least one further sensor comprises an accelerometer.

### Claim 3 (depends on 1)

The apparatus according to claim 1, wherein said at least one further sensor comprises a heart rate sensor arranged to measure a heart rate of the person.

### Claim 4 (depends on 1)

The apparatus according to claim 1, wherein said at least one further sensor comprises a temperature sensor arranged to measure a body temperature of the person.

### Claim 5 (depends on 1)

The apparatus according to claim 1, wherein said at least one further sensor comprises a pH sensor arranged to measure an acidity of the blood of the person.

### Claim 6 (depends on 1)

The apparatus according to claim 1, wherein said at least one further sensor comprises a ketone sensor arranged to detect ketone bodies in the body of the person.

### Claim 7 (depends on 1)

The apparatus according to claim 1, wherein said at least one further sensor comprises a GPS receiver arranged to detect a location of the person.

### Claim 8 (depends on 1)

The apparatus according to claim 1, wherein said at least one further sensor comprises a skin resistance sensor arranged to measure galvanic resistance of the skin of the person.

### Claim 9 (depends on 1)

The apparatus according to claim 1, wherein any of said at least one glucose sensor and/or said at least one further sensor is arranged to be attached to the body of the person.

### Claim 10 (depends on 9)

The apparatus according to claim 9, wherein the at least one substance is introduced into the body by a cannula or a catheter to be inserted into the body, wherein the cannula or the catheter comprises any of said at least one glucose sensor and/or said at least one further sensor.