# US 11,439,746 B2 · Implantable infusion system > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,439,746 B2 - Document ID: US11439746B2 - Status: Granted - Kind: B2 - Application number: 15/736,353 - Filed: 2016-06-17 - Published: 2018-06-07 - Granted: 2022-09-13 - Earliest claimed: 2016-06-17 - Assignees: Ipadic B.V. - Applicants: Ipadic B.V. - Inventors: Adri Marinus Blomme; Jozef Augustinus Elisabeth Spaan - Web page: https://patentgrep.com/patent/US11439746B2 ## CPC - A61M 5/14276: {specially adapted for implantation} - A61M 5/1413: {Modular systems comprising interconnecting elements} - A61M 39/04: having pierceable self-sealing members - A61M 2005/14513: {with secondary fluid driving or regulating the infusion} - A61M 2039/0238: {having means for locating the implanted device to insure proper injection, e.g. radio-emitter, protuberances, radio-opaque markers} - A61M 2205/3337: Controlling, regulating pressure or flow by means of a valve by-passing a pump - A61M 2205/3507: with implanted devices, e.g. external control - A61M 2205/3538: using electrical conduction through the body of the patient - A61M 2205/52: with memories providing a history of measured variating parameters of apparatus or patient - A61M 2205/8206: battery-operated - A61M 2210/1017: Peritoneal cavity - A61M 2230/201: Glucose concentration - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract A system to be implanted in a living body for supplying medical substance, such as insulin. The system has a first module (1) having an inlet port (5) for receiving a transcutaneous injection of the medical substance, a second module (2) having a reservoir for storing the medical substance; a first tube (3) allowing the medical substance to flow between the first module and the second module; and a catheter (4) for releasing the stored medical substance into the living body. The first tube (3) allows the first module and second module to be implanted at different locations in the living body. ## Claims ### Claim 1 A system adapted to be implanted in a living body for supplying medical substance, the system comprising: a first module having an inlet port for receiving a transcutaneous injection of the medical substance; a second module having a reservoir for storing the medical substance; a first tube, arranged to allow the medical substance to flow between the first module and the second module; an electrically powered pump; and a catheter for releasing the stored medical substance into the living body, wherein the first tube is arranged to allow the first module and second module to be implanted at different locations in the living body, wherein the catheter is connected to the first module, wherein the first module comprises an electrically controlled valve connected to the inlet port, to the first tube and to the catheter, the valve having three modes of operation, wherein in a first mode the valve connects the first tube to the catheter for supplying medical substance from the reservoir to the catheter, wherein in a second mode the valve connects the inlet port to the first tube for filling the reservoir and wherein in a third mode the valve directly connects the inlet port to the catheter for rinsing the catheter or to enable use of an external pump. ### Claim 2 (depends on 1) The system of claim 1, wherein the first tube is arranged to conduct the medical substance from and to the first module and the second module. ### Claim 3 (depends on 1) The system of claim 1, wherein the first module, is provided with a power supply for supplying an electronic power to the system. ### Claim 4 (depends on 1) The system of claim 1, wherein the first module, is provided with a rechargeable battery, and a charging circuit for receiving a contactless charging signal from a charging device, wherein the charging circuit is provided in or close to the inlet port. ### Claim 5 (depends on 4) The system of claim 4, the system further comprising a charging device for emitting a charging signal for the charging circuit. ### Claim 6 (depends on 1) The system of claim 1, wherein the first tube provides an electrical connection between the first module to the second module. ### Claim 7 (depends on 6) The system of claim 6, wherein the second module comprises the electrically powered pump for pumping the medical substance from and/or to the reservoir. ### Claim 8 (depends on 1) The system of claim 1, further comprising a glucose sensor for measuring a value representing a level of blood sugar, wherein the system is arranged to control release of the medical substance via the catheter in response to the measured value. ### Claim 9 (depends on 1) The system of claim 1, wherein a second housing of the second module has a closed-off an internal volume that receives the reservoir and wherein the reservoir is arranged to change a shape in dependence of an accumulated release of the medical substance, wherein the internal volume further is filled with a material adapted to transform between a liquid phase and a gas phase in in dependence of the internal volume. ### Claim 10 (depends on 1) The system of claim 1, wherein the first module is arranged in a first housing, wherein the inlet port comprises a self-sealing material. ### Claim 11 (depends on 10) The system of claim 10, wherein the inlet port is one or more of: dome-shaped; positioned on a generally flat side of the first housing; shaped to extend from the first housing. ### Claim 12 (depends on 10) The system of claim 10, wherein the inlet port towers from the first housing in a range between 1 cm and 4 cm. ### Claim 13 (depends on 1) The system of claim 1, wherein the first module comprises a control circuit for controlling the second module to release the stored medical substance via the catheter. ### Claim 14 (depends on 1) The system of claim 1, wherein the first module is adapted to be positioned subcutaneous and the second module is adapted to be positioned deeper than the first module in the living body. ### Claim 15 (depends on 1) The system of claim 1, wherein the second module is arranged in a second housing, wherein the first tube has a length between 4 cm and 15 cm. ### Claim 16 (depends on 1) The system of claim 1, wherein the first module is arranged in a first housing, the second module is arranged in a second housing, and at least one of the first housing and second housing have a plate-like shape. ### Claim 17 (depends on 1) The system of claim 1, the second housing having a plate-like shape having a general bar shape having a top face and a bottom face and four side faces, wherein the top face and the bottom face are connected to the side faces over two curved edges and over two generally straight edges, wherein the top face and/or the bottom face are curved in a direction perpendicular to the straight edges thereof, the top face and the bottom face having a different curvature. ### Claim 18 (depends on 1) The system of any of claim 1, wherein the first module comprises a magnet or an electromagnetic coil, preferably in or close to the inlet port, to be attracted by an electromagnetic force generated outside the living human body. ### Claim 19 (depends on 18) The system of claim 18, further comprising a locator device for locating the first module by an electromagnetic force. ### Claim 20 A system adapted to be implanted in a living body for supplying medical substance, the system comprising: an inlet port for receiving a transcutaneous injection of the medical substance; an electrically powered pump; a housing, comprising a reservoir for storing the medical substance; and a catheter for releasing the stored medical substance into the living body, wherein the housing has a shape lacking a cylindrical symmetry, and wherein the system further comprises an electrically controlled valve that is fluidly connected to the inlet port, to the reservoir and to the catheter, the valve having three modes of operation, wherein in a first mode the valve connects the first tube to the catheter for supplying medical substance from the reservoir to the catheter, wherein in a second mode the valve connects the inlet port to the first tube for filling the reservoir and wherein in a third mode the valve connects the inlet port to the catheter for rinsing the catheter or to enable use of an external pump. ### Claim 21 A kit of modules, for forming a system adapted to be implanted in a living body for supplying medical substance, the kit comprising: a plurality of modules for forming a first housing for receiving a transcutaneous injection of the medical substance and for releasing the medical substance into the body; and a catheter, to be connected to the first housing, for releasing the stored medical substance into the living body, wherein the plurality of modules comprise two or more interchangeable inlet modules for adapting a length of an extending portion of the first housing. ### Claim 22 (depends on 21) The kit of modules of claim 21, wherein the plurality of modules comprises a valve for controlling a liquid flow.