# US 11,439,726 B2 · Surgical implants

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 11,439,726 B2
- Document ID: US11439726B2
- Status: Granted
- Kind: B2
- Application number: 16/701,840
- Filed: 2019-12-03
- Published: 2020-06-04
- Granted: 2022-09-13
- Earliest claimed: 2018-12-03
- Assignees: Osseomimetic, LLC
- Applicants: OsseoMimetic, LLC
- Inventors: Trevor B. Spence; John L. Ricci
- Web page: https://patentgrep.com/patent/US11439726B2

## CPC

- A61L 27/18: obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- A61B 17/0401: {Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors (A61B17/0642 takes precedence; fixation devices for tendons or ligaments A61F2/0811)}
- A61B 17/7291: {for small bones, e.g. in the foot, ankle, hand or wrist}
- A61B 17/80: Cortical plates {, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates}
- A61B 17/8061: {specially adapted for particular bones (A61B17/70 and A61B17/74 take precedence)}
- A61B 17/8625: {Shanks, i.e. parts contacting bone tissue}
- A61F 2/30771: {applied in original prostheses, e.g. holes or grooves}
- A61F 2/34: Acetabular cups
- A61F 2/3609: {Femoral heads or necks; Connections of endoprosthetic heads or necks to endoprosthetic femoral shafts (A61F2/3601 takes precedence)}
- A61F 2/3859: {Femoral components}
- A61F 2/389: {Tibial components (A61F2/3868 takes precedence)}
- A61F 2/4225: {for feet, e.g. toes}
- A61F 2/4241: {for hands, e.g. fingers}
- A61F 2/4405: {for apophyseal or facet joints, i.e. between adjacent spinous or transverse processes (devices implanted between spinous or transverse processes A61B17/7062)}
- A61F 2/4455: {for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages (intervertebral discs A61F2/442)}
- A61F 2/447: {substantially parallelepipedal, e.g. having a rectangular or trapezoidal cross-section}
- A61F 2/80: Sockets, e.g. of suction type
- A61L 31/06: obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds {(A61L31/041 takes precedence)}
- A61B 2017/00955: {thermoplastic}
- A61B 2017/044: {with a threaded shaft, e.g. screws}
- A61F 2/3094: {Designing or manufacturing processes}
- A61F 2002/0081: {directly machined on the prosthetic surface, e.g. holes, grooves (A61F2/30771 takes precedence)}
- A61F 2002/0086: {for preferentially controlling or promoting the growth of specific types of cells or tissues}
- A61F 2002/3082: {Grooves}
- A61F 2002/30822: {Circumferential grooves}
- A61F 2002/30827: {Plurality of grooves}
- A61F 2002/30828: {parallel}
- A61F 2002/30838: {Microstructures}
- A61F 2002/30925: {etched}
- A61F 2002/3093: {for promoting ingrowth of bone tissue}
- A61F 2002/30985: {using three dimensional printing [3DP]}
- A61F 2002/3611: {Heads or epiphyseal parts of femur}
- A61F 2002/4251: {for metacarpo-phalangeal joints, i.e. MCP or MP joints, e.g. knuckle joints}
- A61F 2002/4256: {for carpo-metacarpal joints, i.e. CMC joints}
- A61L 2400/18: Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
- A61L 2430/02: for reconstruction of bones; weight-bearing implants
- A61L 2430/24: for joint reconstruction
- A61L 2430/38: for reconstruction of the spine, vertebrae or intervertebral discs
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)

## Abstract

A surgical implant having a plastic (e.g., PEEK) component having an exposed surface, wherein at least a portion of the exposed surface has a plurality of parallel microgrooves that (i) enhance bone growth and osseointegration with adjacent bone and, after the osseointegration, (ii) increase pull-out force of the surgical implant from the adjacent bone. In certain embodiments, the microgrooves have widths of less than or equal to 12 micrometers, depths of less than or equal to 12 micrometers, crests of less than or equal to 12 micrometers, and a periodicity of less than or equal to 24 micrometers.

## Claims

### Claim 1

A surgical implant comprising a plastic component having an exterior side surface, an interior side surface, a top surface, and a bottom surface, wherein:
each of the exterior and interior side surfaces has a plurality of vertical, elongated microgrooves and each of the top and bottom surfaces has a plurality of concentric, elongated microgrooves, wherein the vertical and concentric, elongated microgrooves are configured to enhance bone growth and osseointegration with adjacent bone and, after the osseointegration, increase pull-out force of the surgical implant from the adjacent bone, wherein:
each pair of adjacent, elongated microgrooves running along the exterior side surface from the top surface to the bottom surface is separated by a single, contiguous, elongated crest running from the top surface to the bottom surface;
each pair of adjacent, elongated microgrooves running along the interior side surface from the top surface to the bottom surface is separated by a single, contiguous, elongated crest running from the top surface to the bottom surface; and
the elongated microgrooves have widths of less than or equal to 12 micrometers, depths of less than or equal to 12 micrometers, crest widths of less than or equal to 12 micrometers, and a periodicity of less than or equal to 24 micrometers, wherein:
after the surgical implant has been implanted, the top and bottom surfaces are configured to be in direct contact with bone; and
the vertical and concentric, elongated microgrooves are configured to inhibit soft tissue ingrowth across the elongated microgrooves, inhibit scar tissue formation where bone is needed to generate, and induce contact guidance to promote bone growth in the direction of the elongated microgrooves.

### Claim 2 (depends on 1)

The surgical implant of claim 1, wherein the plastic component is the surgical implant.

### Claim 3 (depends on 1)

The surgical implant of claim 1, wherein the surgical implant further comprises a non-plastic component connected to the plastic component.

### Claim 4 (depends on 1)

The surgical implant of claim 1, wherein the plastic component is made of polyetheretherketone (PEEK).

### Claim 5 (depends on 1)

The surgical implant of claim 1, wherein the elongated microgrooves have widths of 4-12 micrometers, depths of 4-12 micrometers, crest widths of 4-12 micrometers, and a periodicity of 8-24 micrometers.

### Claim 6 (depends on 5)

The surgical implant of claim 5, wherein the elongated microgrooves have widths of 8-12 micrometers, depths of 8-12 micrometers, crest widths of 8-12 micrometers, and a periodicity of 16-24 micrometers.

### Claim 7 (depends on 1)

The surgical implant of claim 1, wherein the surgical implant is a spinal fusion implant.

### Claim 8 (depends on 7)

The surgical implant of claim 7, wherein the spinal fusion implant is a cervical spinal fusion implant.

### Claim 9 (depends on 7)

The surgical implant of claim 7, wherein the surgical fusion implant is a lumbar spinal interbody fusion implant.

### Claim 10 (depends on 1)

The surgical implant of claim 1, wherein the surgical implant further comprises a threaded through-hole between the exterior and interior side surfaces.

### Claim 11 (depends on 1)

The surgical implant of claim 1, wherein:
each pair of adjacent, elongated microgrooves running around the top surface is separated by a single, contiguous, elongated crest running around the top surface; and
each pair of adjacent, elongated microgrooves running around the bottom surface is separated by a single, contiguous, elongated crest running around the bottom surface.