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US 11,439,675 B2Granted
Method for treating damage induced by sleep deprivation
AssigneePresident and Fellows of Harvard College
InventorsDragana Rogulja, Alexandra Vaccaro
Life of this patent
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Abstract
Described herein are methods and compositions for the use of treating damage induced by SD. Aspects of the invention relate to administering to a subject in need thereof an agent that reduces reactive oxygen species. In some embodiments, administration of an agent that reduces reactive oxygen species repairs SD-induced damage in the gut.
Claims8
A method for treating gastrointestinal tract damage induced by sleep deprivation (SD), the method comprising:
- administering to an individual who is sleep deprived and has gastrointestinal damage a therapeutically effective amount of a composition comprising a probiotic that reduces reactive oxygen species, wherein the probiotic is selected from the group consisting of:
- Streptococcus thermophilus, Lactobacillus casei, Lactococcus lactis, and Lactobacillus paracasei, or wherein the probiotic is a probiotic with a 16S rRNA sequence having at least 90% sequence identity to a 16S rRNA sequence from Lactococcus lactis.
Dependencies are inferred from the claim text.