# US 11,439,596 B2 · Co-granules of xanthan gum and acacia gum

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- Number: US 11,439,596 B2
- Document ID: US11439596B2
- Status: Granted
- Kind: B2
- Application number: 15/308,697
- Filed: 2015-04-28
- Published: 2017-07-06
- Granted: 2022-09-13
- Earliest claimed: 2014-05-05
- Assignees: Societe D'Exploitation De Produits Pour Les Industries Chimiques Seppic
- Applicants: Societe d'Exploitation de Produits Pour les Industries Chimiques Seppic
- Inventors: Sandra Lefebvre
- Web page: https://patentgrep.com/patent/US11439596B2

## CPC

- A61K 9/205: {Polysaccharides, e.g. alginate, gums; Cyclodextrin}
- A61K 9/1652: {Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin (homeopathic globules A61K9/1623)}
- A61K 47/36: Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)

## Abstract

The invention relates to a co-granule of xanthan gum and acacia gum having an average diameter of between 50 μm and 1000 μm.

## Claims

### Claim 1

A co-granule consisting of:
xanthan gum and acacia gum,
wherein the co-granule has a mean diameter of between 100 μm and 300 μm, and
a density of between 0.35 mg/ml and 0.7 mg/ml,
wherein at most 4 weight % of the particles of the co-granule have a mean diameter of greater than 500 μm and from 65 to 90 weight % of the particles of the co-granule have a mean diameter of greater than 80 μm,
wherein the weight ratio between the xanthan gum and the acacia gum varies from 4/1 to 3/1, and
wherein said co-granule is prepared by spraying a solution of acacia gum onto solid particles of xanthum gum in a fluidized bed by means of a gas stream, and the co-granules are obtained by drying.

### Claim 2 (depends on 1)

The co-granule as claimed in claim 1, wherein the weight ratio between the xanthan gum and the acacia gum is equal to 3/1.

### Claim 3 (depends on 1)

A composition comprising at least one tablet wherein said at least one tablet comprise at least one active ingredient and/or at least one nutritional agent, and from 15 to 50 weight % of the co-granules as defined in claim 1.

### Claim 4 (depends on 3)

The composition as claimed in claim 3, wherein the at least one tablet further comprises at least one excipient the group consisting of: a diluent, a lubricant, and a cohesion agent.

### Claim 5 (depends on 4)

The composition as claimed in claim 4, the at least one tablet comprises, per 100% of its weight, from 20 to 35 weight % of the co-granules, from 0.1 to 60 weight % of an active ingredient and/or of a nutritional agent, from 10 to 50 weight % of the diluent or the cohesion agent, and from 0.5 to 3 weight % of the lubricant.

### Claim 6 (depends on 3)

The composition as claimed in claim 3, wherein the composition is a pharmaceutical, food supplement or dietary composition, having a prolonged-release effect.

### Claim 7 (depends on 3)

A method for preparing a composition as defined in claim 3, comprising at least one step of forming the at least one tablet by direct compression of a mixture comprising from 15% to 50% by weight of the co-granules and the at least one active ingredient and/or the at least one nutritional agent.

### Claim 8 (depends on 7)

The method as claimed in claim 7, wherein the mixture from which the at least one tablet is formed further comprises at least one excipient selected from the group consisting of: a diluent, a lubricant, and a cohesion agent.

### Claim 9 (depends on 7)

The method as claimed in claim 7, wherein the composition is a pharmaceutical composition or a food supplement or dietary composition.

### Claim 10 (depends on 1)

The co-granule of claim 1, wherein the mean diameter is approximately 150 μm.
