Vaginal sustained-release drug delivery system for luteal support, method for preparation and use thereof

Abstract

The present invention relates to a vaginal sustained-release drug delivery system for luteal support and a method for preparation and use thereof. The vaginal sustained-release drug delivery system for luteal support is a progesterone depot-type vaginal ring having a bilayer structure of a core layer and a film layer enclosing the core layer, wherein the core layer is composed of a solid scaffold carrier of medical EVA containing a drug uniformly dispersed therein, and the film layer is composed of a medical EVA material containing no drug. The vaginal sustained-release drug delivery system for luteal support according to the present invention can be used for assisted reproduction and for treatment of functional uterine bleeding, premenstrual syndrome and the like due to luteal phase defect with a significantly improved therapeutic effect.

Dependencies are inferred from the claim text.