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US 11,439,342 B2Granted
Oral food challenge meal formulations
AssigneeReacta Biotech Limited
InventorsClare Mills, Anuradha Balasundaram, Carol Ann Costello, Ivona Baricevic-Jones, Martin Wickham
Life of this patent
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Abstract
This invention relates to kits including novel oral food challenge meal formulations. In particular, the invention also relates to kits including novel oral food challenge meal formulations, wherein the placebo dose formulation is indistinguishable from non-placebo dose formulations.
Claims15
A kit comprising:
- a placebo challenge meal formulation comprising no food allergen;
- and
- a non-placebo challenge meal formulation comprising an allergen, wherein the allergen is present in the non-placebo challenge meal formulation in an amount of more than 10% w/w and less than 25% w/w;
- wherein the placebo and non-placebo challenge meal formulations each comprise:
- 20% w/w to 60% w/w of a matrix formation component, wherein the matrix formation component comprises a starch and a sucrose;
- 10% w/w to 35% w/w of a texturizing component, wherein the texturizing component comprises an oil component and a surfactant;
- and
- 10% w/w to 45% w/w of a flavor/color masking component;
- and
- wherein the placebo challenge meal formulation comprises an additive present in an amount of from about 0.05% w/w to about 1.0 w/w of the placebo food challenge meal formulation, and wherein the additive is selected from the group consisting of:
- maltodextrin, dextrin, cyclodextrin and combinations thereof, and
- wherein, upon reconstitution with water, the placebo and the non-placebo challenge meal formulations each form a mousse.
9 more elements
Dependencies are inferred from the claim text.