Anti-Acanthamoeba contact lens solution
AssigneeSeed Co., Ltd.
InventorsHideyuki Otake, Yoshinori Yanagawa, Hiroyuki Nawase
Life of this patent
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Abstract
The objective of the present invention is to provide a contact lens solution that is safer to eyes such that it has little or no effects on eye tissue and has the versatility that makes the solution applicable to a wide range of contact lenses, while exhibiting desirable anti-Acanthamoeba activity. The objective is achieved by the anti-Acanthamoeba contact lens solution containing a cationic polymer having an average molecular weight in a range of 150,000 to 1,600,000 and having in its molecule a diallyldimethylammonium chloride unit and an inorganic salt.
Claims11
An anti-acanthamoeba contact lens solution comprising a cationic polymer having an average molecular weight in a range of 150,000 to 1,600,000 and having in its molecule a diallyldimethylammonium chloride unit represented by general formula (I):
- wherein n is an integer determined such that the average molecular weight of the polymer is in the range specified above;
- a borate buffer;
- a chelating agent;
- and
- an inorganic salt;
- wherein the cationic polymer is at least a cationic polymer selected from the group consisting of a cationic polymer wherein the polymer unit in its molecule is the diallyldimethylammonium chloride unit, a cationic polymer wherein the polymer units in its molecule are the diallyldimethylammonium chloride unit and an acrylamide unit, a cationic polymer wherein the polymer units in its molecule are the diallyldimethylammonium chloride unit and an acrylic acid unit, and a cationic polymer wherein the polymer units in its molecule are the diallyldimethylammonium chloride unit, an acrylamide unit and an acrylic acid unit;
- wherein the anti-acanthamoeba contact lens solution comprises no biguanide-based disinfectant and no quaternary ammonium-based disinfectant;
- wherein the chelating agent is ethylenediaminetetraacetic acid;
- wherein the inorganic salt is an inorganic salt selected from the group consisting of sodium chloride and potassium chloride or a combination thereof;
- and
- wherein the cationic polymer is present in an amount of from 0.0001 to 0.01 w/v %, the borate buffer is present in an amount of from 0.05 to 1.0 w/v %, the chelating agent is present in an amount of from 0.01 to 0.05 w/v %, and the inorganic salt or the combination thereof is present in a total amount of from 0.75 to 1.0 w/v %.
Dependencies are inferred from the claim text.