# US 11,432,997 B2 · Sterile drug dispensing system and sterile drug dispensing method

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 11,432,997 B2
- Document ID: US11432997B2
- Status: Granted
- Kind: B2
- Application number: 16/478,478
- Filed: 2017-06-27
- Published: 2020-06-18
- Granted: 2022-09-06
- Earliest claimed: 2017-01-17
- Assignees: Harbin Biyan Technology Co., Ltd.
- Applicants: Harbin Biyan Technology Co., Ltd.
- Inventors: Jin Dong Zhang; Wei Zhang
- Web page: https://patentgrep.com/patent/US11432997B2

## CPC

- A61J 1/2082: {for gas filtration}
- A61M 5/1413: {Modular systems comprising interconnecting elements}
- A61J 1/201: {having one piercing end}
- A61M 5/155: pressurised by gas {introduced into the reservoir}
- A61M 5/20: Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically (A61M5/142 takes precedence)
- A61M 5/2053: {Media being expelled from injector by pressurised fluid or vacuum (for infusion A61M5/145, A61M5/155)}
- A61M 5/3148: {Means for causing or aiding aspiration or plunger retraction}
- A61M 5/31566: {Means improving security or handling thereof}
- A61M 2205/7509: for virus
- A61M 2205/7518: bacterial
- B01D 46/0012: {In-line filters}
- B01D 46/10: Particle separators, e.g. dust precipitators, using filter plates, sheets or pads having plane surfaces
- A61J: CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- B01D: SEPARATION (separating solids from solids by wet methods B03B, B03D; by pneumatic jigs or tables B03B; by other dry methods B07; magnetic or electrostatic separation of solid materials from solid materials or fluids, separation by high-voltage electric fields B03C; centrifuges, vortex apparatus B04; presses per se for squeezing-out liquid from liquid-containing material B30B9/02; treatment of water C02F, e.g. softening by ion-exchange C02F1/42; {arrangements of air intake cleaners in gas turbine plants F02C7/05} ; arrangements or mounting of filters in air-conditioning, air-humidification or ventilation F24F13/28)

## Abstract

A sterile drug dispensing system, comprising: an air source output device, a handle and a drug dissolving device; the drug dissolving device is detachably mounted on the handle, the handle being connected to the air source output device by means of a power line and an air pipe, being for use in filtering gas and controlling the gas source output device; the gas source output device is used for outputting and extracting gas. A sterile drug dispensing method, which corresponds to the operating steps of the sterile drug dispensing system.

## Claims

### Claim 1

A sterile drug dispensing method, comprising:
preparing a sterile drug dispensing system comprising:
an air source output device;
a handle;
a filter is disposed in the handle; and
a drug dissolving device detachably mountable on the handle; wherein the drug dissolving device comprises
a needle;
a barrel; and
a rubber stopper disposed inside the barrel;
wherein the handle is connected to the air source output device through a power cord and an air pipe, for filtering air, and controlling the air source output device; wherein the air source output device is used to output and extract air, and
the method further comprising the following steps:
Step S6: inserting the needle of the drug dissolving device into a vial, controlling the rubber stopper in the drug dissolving device to move away from the needle, pumping a liquid medicine in the vial into the drug dissolving device, and pulling out the needle;
Step S7: inserting the needle of the drug dissolving device into a new vial, the new vial being filled with a second liquid medicine or a powder medicine; when the new vial is filled with the second liquid medicine, controlling the rubber stopper in the drug dissolving device to move away from the needle, and pumping the second liquid medicine in the new vial into the drug dissolving device, and pulling out the needle; and when the new vial is filled with the powder medicine, controlling the rubber stopper to move toward the needle, pushing the liquid medicine into the new vial, and pulling out the needle after mixing; and
Step S8: repeating Step S7 until the second liquid medicine or the powder medicine in the new vial is pumped into the drug dissolving device;
reserving a certain distance between the rubber stopper and a front end of the barrel in the drug dissolving device to counter a negative pressure in the vial,
before Step S6, the method further includes Step S5:
Step S5: mounting the drug dissolving device on the handle;
before Step S5, the method further includes the following steps:
Step S1: the air source output device outputting a power air source to the handle, the power air source replacing a front end region of the handle with a clean and sterile environment after passing through the filter in the handle;
Step S2: attaching the drug dissolving device to an inside of the front end of the handle and pushing backwards until a rear end of the drug dissolving device enters the sterile environment at the front end of the handle; and
Step S3: mounting the drug dissolving device rearward on the handle while controlling the air source output device to stop providing the power air source to the handle.

### Claim 2 (depends on 1)

The sterile drug dispensing method in claim 1, wherein, in Step S6 and Step S7, the handle is configured to control the air source output device to extract the air at a rear end of the rubber stopper in the barrel to form a negative pressure environment, so that the rubber stopper moves away from the needle; and the handle is configured to control the air source output device to output air to the rear end of the rubber stopper in the barrel to form a positive pressure environment, so that the rubber stopper moves toward the needle.

### Claim 3 (depends on 2)

The sterile drug dispensing method in claim 2, wherein, in Step S1, the rubber stopper of the drug dissolving device is located at the rear end of the drug dissolving device, and the rear end of the drug dissolving device is on a same plane as the rubber stopper.

### Claim 4 (depends on 3)

The sterile drug dispensing method in claim 3, wherein, in Step S2, after the rear end of the drug dissolving device enters the sterile environment at the front end of the handle, it is left for 1-2 seconds to continue mounting.

### Claim 5 (depends on 4)

The sterile drug dispensing method in claim 4, wherein, in Step S3, when the drug dissolving device is pushed to a groove of the front end of the handle, the drug dissolving device is snapped into the groove of the front end of the handle, and the drug dissolving device is rotated, so as to achieve a snap connection between the drug dissolving device and the handle.

### Claim 6 (depends on 5)

The sterile drug dispensing method in claim 5, wherein, in Step S3, a detection unit is disposed on the handle, for detecting that the drug dissolving device has been mounted on the handle, and controlling the air source output device to stop providing the power air source to the handle.

### Claim 7 (depends on 6)

The sterile drug dispensing method in claim 6, wherein, after Step S3, the method further includes Step S4:
Step S4: the air source output device outputting air, and controlling the rubber stopper to move to an intermediate position of the barrel.

### Claim 8 (depends on 7)

The sterile drug dispensing method in claim 7, wherein, the handle is configured to control the air source output device through buttons, and the buttons are disposed on the handle.