# US 11,432,795 B2 · Alternative anatomical borders of blood vessels and associated devices systems and methods

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- Number: US 11,432,795 B2
- Document ID: US11432795B2
- Status: Granted
- Kind: B2
- Application number: 16/351,175
- Filed: 2019-03-12
- Published: 2019-09-19
- Granted: 2022-09-06
- Earliest claimed: 2018-03-14
- Assignees: Philips Image Guided Therapy Corporation
- Applicants: Volcano Corporation
- Inventors: Fergus Merritt
- Web page: https://patentgrep.com/patent/US11432795B2

## CPC

- A61B 8/085: {for locating body or organic structures, e.g. tumours, calculi, blood vessels, nodules}
- A61B 8/12: in body cavities or body tracts, e.g. by using catheters
- G06T 7/10: Segmentation; Edge detection (motion-based segmentation G06T7/215)
- G16H 30/40: for processing medical images, e.g. editing
- A61B 5/0033: {Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room}
- A61B 5/02007: {Evaluating blood vessel condition, e.g. elasticity, compliance}
- A61B 8/0891: {for diagnosis of blood vessels}
- A61B 8/463: {characterised by displaying multiple images or images and diagnostic data on one display}
- A61B 8/469: {for selection of a region of interest}
- G06T 7/0012: {Biomedical image inspection}
- G06T 2200/24: involving graphical user interfaces [GUIs]
- G06T 2207/10072: Tomographic images
- G06T 2207/10116: X-ray image
- G06T 2207/10132: Ultrasound image
- G06T 2207/20092: Interactive image processing based on input by user
- G06T 2207/20101: Interactive definition of point of interest, landmark or seed
- G06T 2207/30021: Catheter; Guide wire
- G06T 2207/30101: Blood vessel; Artery; Vein; Vascular
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA

## Abstract

The present disclosure relates generally to the imaging of blood vessels, and in particular, to the detection of one or more borders of a blood vessel. In some embodiments, a medical imaging system is configured to detect a primary border of a blood vessel and one or more alternative borders of the blood vessel. For example, in some embodiments, a medical imaging system includes an imaging device configured to obtain an image of a blood vessel, a processing unit, and a user display. The processing unit can be configured to receive the image of the blood vessel and perform an analysis of the image to identify a primary candidate border and an alternative candidate border of the blood vessel. The primary candidate border and alternative candidate border can represent candidates for a single boundary of the blood vessel.

## Claims

### Claim 1

A method for blood vessel border identification, comprising:
obtaining an intravascular image of a blood vessel of a patient with an intravascular imaging catheter positioned inside the blood vessel;
performing, at a processing unit in communication with the intravascular imaging catheter, an analysis of the intravascular image of the blood vessel to identify a plurality of candidate borders of the blood vessel, wherein the plurality of candidate borders comprises a primary candidate border and an alternative candidate border, wherein the primary candidate border and the alternative candidate border represent candidates for a single circumference of the blood vessel;
outputting, to a user display in communication with the processing unit, a first graphical interface comprising:
the intravascular image of the blood vessel;
the primary candidate border overlaid on the intravascular image of the blood vessel; and
a user input selector proximate to the intravascular image of the blood vessel;
receiving, via a user input device in communication with the processing unit, a selection of the user input selector; and
outputting, in response to the selection, a second graphical interface to the user display, wherein the second graphical interface comprises:
the intravascular image of the blood vessel;
the alternative candidate border overlaid on the intravascular image of the blood vessel; and
the user input selector proximate to the intravascular image of the blood vessel,
wherein the primary candidate border is visually displayed in a first manner in the first graphical interface and the alternative candidate border is visually displayed in a different, second manner in the second graphical interface.

### Claim 2 (depends on 1)

The method of claim 1, wherein the selection of the user input selector in the first graphical interface corresponds to rejecting the primary candidate border.

### Claim 3 (depends on 1)

The method of claim 1, further comprising receiving, via the user interface input device, a further selection of the user input selector in the second graphical interface; and
in response to the further selection, accepting the alternative candidate border.

### Claim 4 (depends on 1)

The method of claim 1, wherein the primary candidate border is associated with a first criterion of the analysis and the alternative candidate border is associated with a second criterion of the analysis that is different from the first criterion.

### Claim 5 (depends on 4)

The method of claim 4, further comprising:
obtaining a plurality of intravascular images of the blood vessel; and
performing, at the processing unit, an analysis of each of the plurality of intravascular images of the blood vessel,
wherein the performing the analysis comprises propagating the criterion associated with either the primary candidate border or the alternative candidate border to each of the plurality of intravascular images of the blood vessel to identify the circumference in each of the plurality of intravascular images of the blood vessel.

### Claim 6

A blood vessel border identification system, comprising:
an intravascular imaging catheter configured to obtain an intravascular image of a blood vessel of a patient while the intravascular imaging catheter is positioned inside the blood vessel;
a processing unit configured for communication with the intravascular imaging catheter, a user input device, and a user display, wherein the processing unit is configured to:
receive the intravascular image of the blood vessel;
perform an analysis of the intravascular image of the blood vessel to identify a plurality of candidate borders of the blood vessel, wherein the plurality of candidate borders comprises a primary candidate border and an alternative candidate border, wherein the primary candidate border and alternative candidate border represent candidates for a single circumference of the blood vessel;
output, to the user display, a first graphical interface comprising:
the intravascular image of the blood vessel;
the primary candidate border overlaid on the intravascular image of the blood vessel; and
a user input selector proximate to the intravascular image of the blood vessel;
receive, via the user input device, a selection of the user input selector; and
output, in response to the selection, a second graphical interface to the user display, wherein the second graphical interface comprises:
the intravascular image of the blood vessel;
the alternative candidate border overlaid on the intravascular image of the blood vessel; and
the user input selector proximate to the intravascular image of the blood vessel,
wherein the primary candidate border is visually displayed in a first manner in the first graphical interface and the alternative candidate border is visually displayed in a different, second manner in the second graphical interface.

### Claim 7 (depends on 6)

The system of claim 6, wherein the selection of the user input selector in the first graphical interface corresponds to rejecting the primary candidate border.

### Claim 8 (depends on 6)

The system of claim 6, wherein the primary candidate border is associated with a first criterion of the analysis, and the alternative candidate border is associated with a second criterion of the analysis different from the first criterion.

### Claim 9 (depends on 8)

The system of claim 8,
wherein the intravascular imaging catheter is configured to obtain a plurality of intravascular images of the blood vessel, and
wherein the processing unit is configured to propagate the criterion associated with either the primary candidate border or the alternative candidate border to each of the plurality of intravascular images of the blood vessel to identify the circumference in each of the plurality of intravascular images of the blood vessel.

### Claim 10 (depends on 6)

The system of claim 6, wherein the primary candidate border is the only candidate border of the plurality of candidate borders displayed in the first graphical interface and the alternative candidate border is the only candidate border of the plurality of candidate borders displayed in the second graphical interface.

### Claim 11 (depends on 6)

The system of claim 6, further comprising:
the user input device; and
the user display.

### Claim 12 (depends on 6)

The system of claim 6, wherein the processing unit is further configured to:
receive, via the user interface input device, a further selection of the user input selector in the second graphical interface; and
in response to the further selection, accept the alternative candidate border.