# US 11,432,743 B2 · Respiration device with presetting of a patients individual pressure profile > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,432,743 B2 - Document ID: US11432743B2 - Status: Granted - Kind: B2 - Application number: 15/854,027 - Filed: 2017-12-26 - Published: 2018-06-28 - Granted: 2022-09-06 - Earliest claimed: 2016-12-23 - Assignees: Loewenstein Medical Technology S.A. - Applicants: Loewenstein Medical Technology S.A. - Inventors: Benno Doemer; Ruediger Alshut; Matthias Schwaibold - Web page: https://patentgrep.com/patent/US11432743B2 ## CPC - A61B 5/087: Measuring breath flow - A61B 5/082: {Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath (A61B5/083, A61B5/091 take precedence)} - A61B 5/097: Devices for facilitating collection of breath or for directing breath into or through measuring devices - A61M 16/024: {including calculation means, e.g. using a processor} - A61M 16/026: {specially adapted for predicting, e.g. for determining an information representative of a flow limitation during a ventilation cycle by using a root square technique or a regression analysis} - A61M 16/0605: {Means for improving the adaptation of the mask to the patient} - A61M 16/0003: {Accessories therefor, e.g. sensors, vibrators, negative pressure} - A61M 2016/0036: {in the breathing tube and used in both inspiratory and expiratory phase} - A61M 2205/3334: Measuring or controlling the flow rate - A61M 2205/502: User interfaces, e.g. screens or keyboards - A61M 2205/52: with memories providing a history of measured variating parameters of apparatus or patient - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract Disclosed is a device for respiration with at least one pressurized gas source for respiratory gas and a sensor unit for determination of respiratory gas pressure and/or flow rate and/or volume and a control unit. The control unit records an individual breathing pattern of a patient and from this forms an individual pressure profile for the patient which is provided by the pressurized gas source. ## Claims ### Claim 1 A device for respiration, wherein the device comprises at least one pressurized gas source for respiratory gas, a sensor unit for determining respiratory gas flow rate, a control unit, and a memory, the control unit comprising: a curve analyzer, which is configured to determine and store in the memory a curve of at least one signal that is determined by the sensor unit, a transform function, which is configured to convert by at least one mathematical mapping the stored curve of the at least one signal determined by the sensor unit into a pressure profile and further is configured to use an individual breathing pattern of a patient, which is stored and formed as a function of at least two curves of the at least one signal, and a current breathing pattern of the patient, from the curve of the at least one signal, a pressure profile applicator, which is configured to actuate the pressurized gas source as a function of the pressure profile provided by the transform function; and (i) wherein the device further comprises a cutout unit as well as a breathing pattern analyzer and/or a contour analyzer and the cutout unit is designed and set up to send defined time periods or time periods recognized from the curve of the at least one signal from the memory to the breathing pattern analyzer and/or to the contour analyzer and/or (ii) wherein the control unit further comprises a contour analyzer which is configured to recognize, as breathing states or respiration states, an inspiration and/or an expiration and/or a patient trigger and/or a volume and/or an I to E ratio and/or artifacts and/or mouth expiration and/or Cheyne-Stokes breathing. ### Claim 2 (depends on 1) The device of claim 1, wherein the control unit is configured to convert the curve of respiratory gas flow rate as a current breathing pattern of a patient into the pressure profile and to actuate the pressurized gas source as a function of the pressure profile. ### Claim 3 (depends on 1) The device of claim 1, wherein the transform function is additionally configured to use pre-settings of a user. ### Claim 4 (depends on 1) The device of claim 1, wherein the sensor unit is configured to record respiratory gas pressure and/or flow rate and/or volume with a resolution of at least 40 Hz. ### Claim 5 (depends on 1) The device of claim 1, wherein the control unit is configured to store the curve of the at least one signal in the memory with reduced resolution of less than 40 Hz. ### Claim 6 (depends on 1) The device of claim 1, wherein the device further comprises a cutout unit as well as a breathing pattern analyzer and/or a contour analyzer and the cutout unit is designed and set up to send defined time periods or time periods recognized from the curve of the at least one signal from the memory to the breathing pattern analyzer and/or to the contour analyzer. ### Claim 7 (depends on 1) The device of claim 1, wherein the control unit further comprises a contour analyzer which is configured to recognize, as breathing states or respiration states, an inspiration and/or an expiration and/or a patient trigger and/or a volume and/or an I to E ratio and/or artifacts and/or mouth expiration and/or Cheyne-Stokes breathing. ### Claim 8 (depends on 7) The device of claim 7, wherein the contour analyzer is configured to recognize certain breathing states or respiration states by pattern comparison. ### Claim 9 (depends on 1) The device of claim 1, wherein the control unit further comprises a breathing pattern analyzer, the breathing pattern analyzer or the transform function being configured to use a current curve of the at least one signal and an individual breathing pattern stored in the memory. ### Claim 10 (depends on 1) The device of claim 1, wherein the transform function is configured to convert, by the at least one mathematical mapping, an individual breathing pattern into the pressure profile, and in doing so also considers pre-settings of a user which are entered into the memory by an operating element or an operating and information system or an interface, and wherein the pressure profile considers the individual breathing pattern and pre-settings of a user. ### Claim 11 (depends on 10) The device of claim 10, wherein the pressure profile applicator is configured to actuate the pressurized gas source as a function of the pressure profile in such a way that an optimized synchronization with a patient's own breathing occurs. ### Claim 12 (depends on 10) The device of claim 10, wherein the pressure profile applicator is configured to actuate the pressurized gas source as a function of the pressure profile in such a way that a breathing effort of a patient is minimized. ### Claim 13 (depends on 10) The device of claim 10, wherein the pressure profile applicator is configured to actuate the pressurized gas source as a function of the pressure profile in such a way that a formation of an intrinsic PEEP is prevented. ### Claim 14 (depends on 10) The device of claim 10, wherein the pressure profile applicator is configured to actuate the pressurized gas source as a function of the pressure profile in such a way that an anticyclic servoventilation occurs. ### Claim 15 (depends on 10) The device of claim 10, wherein the pressure profile applicator is configured to actuate the pressurized gas source as a function of the pressure profile in such a way that a predetermined tidal volume is achieved. ### Claim 16 (depends on 1) The device of claim 1, wherein the pressure profile comprises a sequence of pressure levels and/or pressure waveforms and/or pressure plateaus and/or pressure ramps, substantially reflecting, at least in segments, corresponding segments of the respiration of a patient from the curve of the at least one signal and/or a breathing pattern. ### Claim 17 (depends on 16) The device of claim 16, wherein the corresponding segments include a frequency and/or an I/E ratio and/or a minute volume and/or inspirations and expirations. ### Claim 18 A device for respiration, wherein the device comprises at least one pressurized gas source for respiratory gas, a sensor unit for determining respiratory gas flow rate, a control unit, and a memory, the control unit comprising: a curve analyzer configured to sense, analyze and store in the memory a curve of at least one signal which stands in connection with or is the respiratory gas flow rate, a cutout unit configured to select one or more defined time periods recognized from the curve, of the curve of the at least one signal and to send them to a breathing pattern analyzer and/or a contour analyzer, a contour analyzer configured to recognize from the curve of the at least one signal of a current time period a presence or absence of certain breathing states or respiration states, a breathing pattern analyzer configured to ascertain an individual breathing pattern of a patient from at least two curves of the at least one signal, a transform function configured to convert by at least one mathematical mapping the curve of the at least one signal determined by the sensor unit into a pressure profile and further configured to use the individual breathing pattern of the patient, which is stored and formed as a function of at least two curves of the at least one signal, and a current breathing pattern of the patient, from the curve of the at least one signal, a pressure profile applicator configured to actuate the pressurized gas source as a function of the pressure profile provided by the transform function. ### Claim 19 A device for respiration, wherein the device comprises at least one pressurized gas source for respiratory gas, a sensor unit for determining respiratory gas flow rate, a control unit, and a memory, the control unit comprising: a curve analyzer configured to sense, analyze and store in the memory a curve of at least one signal which stands in connection with flow rate, a cutout unit configured to select one or more defined time periods recognized from the curve, of the curve of at least one signal stored in the memory and to send them to a breathing pattern analyzer and a contour analyzer, a contour analyzer configured to recognize from the curve of the at least one signal of a current time period that was sent to it by the cutout unit a presence or absence of certain acute breathing states or respiration states, a breathing pattern analyzer configured to ascertain an individual breathing pattern of a patient from at least two curves that were sent to it by the cutout unit, a transform function configured to convert by at least one mathematical mapping the curve of the at least one signal determined by the sensor unit into a pressure profile which is valid for a current or following breath and further configured to use the individual breathing pattern of a patient, which is stored and formed as a function of at least two curves of the at least one signal, and a current breathing pattern of the patient, from the curve of the at least one signal, a pressure profile applicator configured to use results provided by the curve analyzer to optimize a specified pressure profile to a curve of a breath and to send a nominal pressure to the pressure source. ### Claim 20 (depends on 19) The device of claim 19, wherein the transform function is configured to convert, by the at least one mathematical mapping, an individual breathing pattern into the pressure profile, and in doing so also considers pre-settings of a user which are entered into the memory by an operating element or an operating and information system or an interface, wherein the pressure profile considers the individual breathing pattern and pre-settings of a user, and wherein the pressure profile applicator is configured to actuate the pressurized gas source as a function of the pressure profile in such a way that an optimized synchronization with a patient's own breathing occurs and/or a breathing effort of a patient is minimized and/or a formation of an intrinsic PEEP is prevented and/or a predetermined minute ventilation is achieved and/or an anticyclic servoventilation occurs and/or a predetermined tidal volume is achieved.