Visual stimuli maze test for detecting visual abnormalities in prodromal Alzheimer's disease and in Alzheimer's disease

A maze for evaluating a rodent, the maze comprising:

• a plurality of rooms, each of the plurality of rooms comprising a floor plate, a base floor, side walls, a removable cover on top of the side walls, and a set of light emitting diodes (LEDs), the set of LEDs positioned below the floor plate and within an LED insertion gap between the floor plate and the base floor;
• w herein the plurality of rooms are configured to allow the rodent to traverse between the rooms;
• w herein, in each of the plurality of rooms, the set of LEDs, the respective removable cover, and the respective floor plates are configured to provide homogenized illumination of an entirety of the respective arm;
• and
• w herein each set of LEDs errits light at different wavelength ranges.

A maze for evaluating a rodent, the maze comprising:

• a first room including a first visual marker;
• a second room including a second visual marker;
• a third room including a third visual marker;
• and
• a fourth room including a fourth visual marker;
• each of the first, second, third, and fourth rooms including side walls, a base floor, a floor plate, and an insertion gap between the floor plate and the base floor, the floor plate positioned above the base floor;
• wherein each of the first, second, third, and fourth visual markers is a set of LEDs;
• wherein each of the first, second, third, and fourth visual markers is positioned in the respective insertion gap of the first, second, third, and fourth rooms;
• wherein the first, second, third, and fourth rooms are configured to allow the rodent to traverse between the rooms;
• wherein in each room, each of the first visual marker, the second visual marker, the third visual marker, and the fourth visual marker is configured to illuminate the respective floor plate to provide a first contrast difference between the respective side walls and the respective floor plate;
• and
• wherein each of the first, second, third, and fourth visual markers are configured to have a second contrast difference with respect to any of the other three visual markers.