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US 11,420,947 B2Granted
(S)-n-hydroxy-2-(2-(4-methoxyphenyl)butanamido)thiazole-5-carboxamide and pharmaceutically acceptable salts thereof
AssigneeTranslational Drug Development, LLC
InventorsTong Wang, Stephen Gately
Life of this patent
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Abstract
The invention relates to the compound (S)-n-hydroxy-2-(2-(4-methoxyphenyl) butanamido)thiazole-5-carboxamide, which is a novel histone deacetylase inhibitor. The invention further relates to the use of the compound for the inhibition of histone deacetylating activities of HDAC isoforms and treatment of histone deacetylase (HDAC)-associated diseases. The invention also relates to the pharmaceutical compositions and the making of the pharmaceutical compositions comprising the compound.
Claims8
A pharmaceutical composition in which the active ingredient consists of:
- (S)-N-hydroxy-2-(2-(4-methoxyphenyl)butanamido)thiazole-5-carboxamide, or a pharmaceutically acceptable salt or solvate thereof.
Dependencies are inferred from the claim text.