# US 11,413,138 B2 · Nasal implant

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- Number: US 11,413,138 B2
- Document ID: US11413138B2
- Status: Granted
- Kind: B2
- Application number: 16/495,052
- Filed: 2018-03-16
- Published: 2020-05-21
- Granted: 2022-08-16
- Earliest claimed: 2017-03-17
- Assignees: Cerhum SA
- Applicants: Cerhum SA
- Inventors: Grégory Nolens; Charles Wolf; Giancarlo Cantella; Thibaut Breuls De Tiecken
- Web page: https://patentgrep.com/patent/US11413138B2

## CPC

- A61F 2/186: {Nose parts}
- A61L 27/12: Phosphorus-containing materials, e.g. apatite
- A61L 27/10: Ceramics or glasses
- A61L 27/56: Porous materials, {e.g. foams or sponges}
- A61F 2240/001: Designing or manufacturing processes
- A61F 2310/00293: containing a phosphorus-containing compound, e.g. apatite
- B33Y 10/00: Processes of additive manufacturing
- B33Y 50/02: for controlling or regulating additive manufacturing processes
- B33Y 70/00: Materials specially adapted for additive manufacturing
- B33Y 80/00: Products made by additive manufacturing
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)
- B33Y: ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING

## Abstract

Nasal implant obtained by additive manufacturing, comprising a main portion and a return portion connected by an intermediate portion, the main and return portions forming an angle of between 25° and 90°, said implant is made from a biocompatible ceramic of synthetic origin; said implant has an average macroporosity characterized by: a density of material of between 20% and 95% by volume, said density of material being higher in said intermediate portion than in said main portion; cavities defining sections of cavities, said sections of cavities each having a diameter of between 0.3 mm and 1 mm; said sections of cavities each having an area and a form substantially equal over the entire implant.

## Claims

### Claim 1

A nasal implant, comprising:
a main portion,
a return portion, and
an intermediate portion;
said main portion and said return portion being connected by said intermediate portion;
said main portion, said return portion and said intermediate portion including pores and being macroporous or partially macroporous,
said main portion and return portion forming an angle of between 25° and 90°,
wherein said implant is made from a biocompatible ceramic of synthetic origin;
wherein said implant has an average macroporosity between 5% and 80%;
wherein said macroporosity is lower in said intermediate portion than in said main portion; and
wherein said pores are cavities at least partially delimited by lateral walls defining sections of cavities, said sections of cavities each having an extension such that it is possible to inscribe each of said sections of cavities in a circle having a diameter of between 0.3 mm and 1 mm.

### Claim 2 (depends on 1)

The nasal implant according to claim 1, wherein said biocompatible ceramic comprises a synthetic bioceramic.

### Claim 3 (depends on 1)

The nasal implant according to claim 1, wherein the biocompatible ceramic comprises a calcium phosphate composition lying between 0 and 100%.

### Claim 4 (depends on 1)

The nasal implant according to claim 1, wherein the biocompatible ceramic comprises a hydroxyapatite composition lying-between 10% and 60%.

### Claim 5 (depends on 1)

The nasal implant according to claim 1, wherein the biocompatible ceramic comprises a tricalcium phosphate composition lying between 40% and 90%.

### Claim 6 (depends on 1)

The nasal implant according to claim 1, wherein said average macroporosity of the implant is between 20% and 50%.

### Claim 7 (depends on 1)

The nasal implant according to claim 1, characterized in that the average macroporosity of the return portion is higher than that of the intermediate portion.

### Claim 8 (depends on 1)

The nasal implant according to claim 1, characterized in that the cavities of the main portion are parallel to each other.

### Claim 9 (depends on 1)

The nasal implant according to claim 1, characterized in that the cavities of the intermediate portion are parallel to each other.

### Claim 10 (depends on 1)

The nasal implant according to claim 1, characterized in that the cavities of the return portion are parallel to each other.

### Claim 11 (depends on 4)

The nasal implant according to claim 4, characterized in that the biocompatible ceramic comprises a hydroxyapatite composition lying between 25% and 45%.

### Claim 12 (depends on 5)

The nasal implant according to claim 5, characterized in that the biocompatible ceramic comprises a tricalcium phosphate composition lying between 55% and 75%.

### Claim 13 (depends on 6)

The nasal implant according to claim 6, characterized in that said density of material of said average macroporosity of the implant is between 60% and 75%.

### Claim 14

A nasal implant, comprising:
a main portion,
a return portion, and
an intermediate portion;
said main portion and said return portion being connected by said intermediate portion;
said main portion and return portion forming an angle of between 25° and 90°,
wherein:
said implant is made from a biocompatible ceramic of synthetic origin; and wherein
said implant has an average macroporosity between 5% and 80%;
said macroporosity is lower in said intermediate portion than in said main portion;
wherein pores are cavities at least partially delimited by lateral walls defining sections of cavities, said sections of cavities each having an extension such that it is possible to inscribe each of said sections of cavities in a circle having a diameter of between 0.3 mm and 1 mm;
wherein porosity of the implant is connected such that a route exists between the pores over whole of the implant without passing outside the implant.

### Claim 15

A nasal implant, comprising:
a main portion,
a return portion, and
an intermediate portion;
said main portion and said return portion being connected by said intermediate portion;
said main portion and return portion forming an angle of between 25° and 90°,
wherein:
said implant is made from a biocompatible ceramic of synthetic origin; and wherein
said implant has an average macroporosity between 5% and 80%;
said macroporosity is lower in said intermediate portion than in said main portion;
wherein the pores are cavities at least partially delimited by lateral walls defining sections of cavities, said sections of cavities each having an extension such that it is possible to inscribe each of said sections of cavities in a circle having a diameter of between 0.3 mm and 1 mm; and
wherein average macroporosity of the return portion is greater than that of the intermediate portion.
