Portable organic molecular sensing device and related systems and methods

A method of detecting an analyte associated with an organic molecule in a liquid and/or solid substance, the method comprising:

• piercing a test chamber wall with a probe to deposit a sample from the probe into a liquid volume of test solution including an analytical reagent contained in the test chamber;
• mixing the sample with the test solution to form a test mixture in the test chamber;
• exciting at least one characteristic of the test mixture in the test chamber, wherein the at least one characteristic includes one or more of magnetic, electrical, and optical characteristics;
• and
• sensing a temporal pattern of the one or more characteristics of the test mixture in the test chamber, wherein said temporal pattern comprises a variation in the at least one characteristic of the test mixture across a period of time, which is indicative of a reaction between the analyte and the analytical reagent.