Method for oxidative cleavage of compounds with unsaturated double bond

A method for oxidative cleavage of a compound with an unsaturated double bond, comprising the steps of:

• (A) providing a compound (I) with an unsaturated double bond, a trifluoromethyl-containing reagent, and a catalyst;
• wherein, R1 and R2 are each independently H, C1-20 alkyl, C3-20 cycloalkyl, C6-18 aryl, or C4-18 heteroaryl, or R1 and R2 are fused to be C6-18 aralkyl;
• R3 is H, C1-10 alkyl, C3-10 cycloalkyl, C6-10 aryl, or C4-10 heteroaryl, with the proviso that R1, R2 and R3 are not H at the same time;
• wherein the catalyst is represented by Formula (II):
• M(O)mL1yL2z (II)
• wherein, M is a metal selected from the group consisting of IVB, VB, VIB, and actinides;
• L1 and L2 are each a ligand;
• m and y are integers greater than or equal to 1;
• and
• z is an integer greater than or equal to 0;
• (B) mixing the compound with the unsaturated double bond and the trifluoromethyl-containing reagent to perform an oxidative cleavage of the compound with the unsaturated double bond by using the catalyst in air or under oxygen atmosphere condition to obtain a compound represented by Formula (III):