Enhanced monitoring method in a drug containers handling line and drug containers handling line thereof

A drug handling line comprising:

• a processing and control unit, wherein the processing and control unit stores a batch number relating to a predetermined batch of containers to be handled by the handling line;
• at least one identifier, wherein the at least one identifier is unique for each container and applied to each container, each identifier being stored and associated to a unique container in said processing and control unit;
• at least one identifier reader placed along the handling line, wherein the at least one identifier reader is configured to read the identifier of each container, wherein the at least one identifier reader is positionable at a plurality of locations within the drug handling line;
• and
• a selector configured to perform one of the actions from a group consisting of discarding, rejecting, or blocking a container in case of negative correspondence between the at least one identifier and the batch number relating to the batch being processed in the handling line, wherein the selector is located upstream of a filling station;
• and
• a plurality of processing stations, wherein the plurality of processing stations are configured to sterilize and inspect each container by visually scanning each container.

A method for reconciliation in a drug inspection line comprising the step of:

• providing a predetermined batch of containers to be handled along a handling line;
• providing a batch number relating to the predetermined batch of containers to be handled;
• providing each one of said containers with a unique identifier differentiating and/or identifying each container;
• sterilizing each of said containers and filling each of said sterilized containers with a drug, at a filling station within the handling line, after each of said sterilized containers is provided with a unique identifier;
• storing and associating each unique identifier with said batch number by a processing and control unit, before starting a handling step of each container;
• and
• scanning and weighing one or more filled sterilized containers with at least one identifier reader at an inspection station, so as to check the correspondence between the batch number being processed and filled container, in order to perform reconciliation, by validating or rejecting in real time each container with respect to a predetermined batch being processed by the drug inspection line.

A method for reconciliation in a drug filling line comprising the step of:

• providing a batch number relating to a predetermined batch of containers to be handled;
• providing each one of said containers with a unique identifier differentiating and/or identifying each container;
• sterilizing each of said containers and filling each of said sterilized containers with a drug, at a filling station within the drug filling line, after each of said sterilized containers is provided with a unique identifier;
• storing and associating each unique identifier with said batch number by a processing and control unit, before starting a handling step of each sterilized container;
• and
• scanning each of said sterilized containers by using at least one identifier reader, before each of said sterilized containers are filled with a drug, to reconcile the batch number being processed and the unique identifier of each empty sterilized container by validating or rejecting in real time each sterilized container with respect to the predetermined batch of sterilized containers being processed by the drug filling line.