Engineered phenylalanine ammonia lyase polypeptides
AssigneeCodexis, Inc.
InventorsGjalt W. Huisman, Nicholas J. Agard, Benjamin Mijts, Jonathan Vroom, Xiyun Zhang
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Abstract
The present invention provides engineered phenylalanine ammonia-lyase (PAL) polypeptides and compositions thereof, as well as polynucleotides encoding the engineered phenylalanine ammonia-lyase (PAL) polypeptides.
Claims31
An engineered polynucleotide encoding an engineered polypeptide comprising an amino acid sequence having at least 90% sequence identity to reference sequence SEQ ID NO:4, wherein said amino acid sequence comprises an amino acid residue selected from alanine, aspartic acid, and glutamine at position 308, wherein said positions in said amino acid sequence are in reference to SEQ ID NO:4.
Dependencies are inferred from the claim text.