# US 11,399,813 B2 · Biopsy syringe > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,399,813 B2 - Document ID: US11399813B2 - Status: Granted - Kind: B2 - Application number: 16/072,311 - Filed: 2017-01-27 - Published: 2019-01-31 - Granted: 2022-08-02 - Earliest claimed: 2016-01-28 - Assignees: Totle Development Aps - Applicants: Totle Development Aps - Inventors: Morten Gulev; Karsten Videbaek; Bjarne Andersen; Per Rosenberg Jensen - Web page: https://patentgrep.com/patent/US11399813B2 ## CPC - A61B 10/0283: {with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe (A61B10/025, A61B10/0266 take precedence)} - A61B 5/15003: {for venous or arterial blood} - A61B 5/150213: {Venting means} - A61B 5/150221: {Valves} - A61B 5/150236: {Pistons, i.e. cylindrical bodies that sit inside the syringe barrel, typically with an air tight seal, and slide in the barrel to create a vacuum or to expel blood} - A61B 5/150244: {Rods for actuating or driving the piston, i.e. the cylindrical body that sits inside the syringe barrel, typically with an air tight seal, and slides in the barrel to create a vacuum or to expel blood} - A61B 5/153: {Devices} specially adapted for taking samples of venous or arterial blood, e.g. with syringes - A61B 10/0045: {Devices for taking samples of body liquids} - A61B 10/0233: {Pointed or sharp biopsy instruments} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract The present disclosure relates to a needle extraction syringe (1) for extracting fluid and/or tissue comprising: a barrel (2) having a proximal lumen (6); and a distal lumen (7) for collecting aspirated fluid/tissue; a plunger (3) having a plunger head (9) sealingly engaged inside the barrel (2); and a plunger body (10) with an internal channel (11); a valve (8) located between the plunger head (9) and a distal end of the syringe inside the barrel (2), separating the proximal lumen (6) and the distal lumen (7) such that air can only flow from the distal lumen (7) to the proximal lumen (6) in a first valve configuration; a sealing element (13) located inside the barrel (2) proximal to the plunger head (9), wherein the plunger head (9) and the sealing element (13) define a vacuum chamber (14) having a variable volume therebetween, wherein the vacuum chamber (14) and the internal channel (11) are fluidly disconnected in relation to each other in a first configuration of the syringe and fluidly connected in a second configuration of the syringe. ## Claims ### Claim 1 A syringe for extracting fluid and/or tissue comprising: a barrel having: a proximal lumen comprising a variable proximal lumen volume; and a distal lumen for collecting aspirated fluid or tissue; a plunger having: a plunger head sealingly engaged inside the barrel; and a plunger body with an internal channel; a valve located between the plunger head and a distal end of the syringe inside the barrel, separating the proximal lumen and the distal lumen such that air can only flow from the distal lumen to the variable proximal lumen volume in a first valve configuration to cause the fluid or tissue to collect in the distal lumen during use, wherein the variable proximal lumen volume is defined by a volume that varies between the valve and the plunger head when the plunger head is moved in a longitudinal direction of the syringe; a sealing element located inside the barrel proximal to the plunger head, wherein a volume between the plunger head and the sealing element define a vacuum chamber having a variable volume therebetween, wherein the vacuum chamber and the internal channel are fluidly disconnected in relation to each other in a first configuration of the syringe and fluidly connected in a second configuration of the syringe. ### Claim 2 (depends on 1) The syringe according to claim 1, the plunger body having a side channel fluidly connecting the internal channel and the vacuum chamber in the second configuration of the syringe. ### Claim 3 (depends on 2) The syringe according to claim 2, wherein the side channel connects the internal channel and the vacuum chamber when the side channel is located on the distal side of the sealing element and connects the internal channel to atmospheric pressure when the side channel is located on the proximal side of the sealing element. ### Claim 4 (depends on 1) The syringe according to claim 1, further comprising a pressure element at the proximal end of the plunger body. ### Claim 5 (depends on 4) The syringe according to claim 4, further comprising a coil spring between the sealing element and the pressure element. ### Claim 6 (depends on 1) The syringe according to claim 1, configured such that repetitively pushing the plunger towards the distal end of the syringe and releasing it towards the proximal end of the syringe accumulates a vacuum. ### Claim 7 (depends on 6) The syringe according to claim 6, wherein the sealing element comprises a one-way valve allowing air to exit the vacuum chamber when the plunger is retracted. ### Claim 8 (depends on 1) The syringe according to claim 1, further comprising a spacing element for preventing that the plunger is moved beyond a predefined limit in the longitudinal direction of the syringe. ### Claim 9 (depends on 1) The syringe according to claim 1, further comprising a vacuum release element at the distal end of the syringe for maintaining and releasing a vacuum generated in the distal lumen through a tip. ### Claim 10 (depends on 9) The syringe according to claim 9, in a loaded configuration, the vacuum release element is configured to maintain the tip of the syringe in a closed position and maintain a generated vacuum in the barrel, and wherein, in a released position, the vacuum release element is configured to maintain the tip of the syringe in an open position. ### Claim 11 (depends on 1) The syringe according to claim 1, further comprising an element configured to release a generated vacuum step-wise in predetermined steps. ### Claim 12 (depends on 1) The syringe according to claim 1, wherein the volume of the internal channel is smaller than the volume of the vacuum chamber. ### Claim 13 (depends on 1) The syringe according to claim 1, wherein the syringe is a fine-needle aspiration syringe. ### Claim 14 (depends on 1) The syringe according to claim 1, wherein the syringe is a core-needle biopsy syringe.