Compounds for detecting and treating Mycoplasma hyopneumoniae
AssigneeAerovirus Technologies Inc.
InventorsNorman J Marchand, Thomas G Caltagirone, Albert Liao
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Abstract
The present invention relates to aptamers, polynucleotides, and nucleic acid molecules, which include a polynucleotide sequence capable of specifically binding polypeptides participating in M. hyopneumoniae infection. Also provided are methods of using nucleic acid molecules, polynucleotides and synthetic antibodies directed there against for detection, treating and neutralization of M. hyopneumoniae infection.
Claims9
A nucleic acid molecule comprising at least one polynucleotide sequence aptamer capable of specifically binding to binding motifs on cleaved segments of surface proteins on M. hyopneumoniae, wherein the at least one polynucleotide sequence is selected from the group consisting of APT3Cooc10 (SEQ ID NO:
- 1), APT3Cooc4 (SEQ ID NO:
- 2), APT3Cooc2 (SEQ ID NO:
- 3), APT3Histo1 (SEQ ID NO:
- 4), APT3Cooc3 (SEQ ID NO:
- 5), APT3Histo2 (SEQ ID NO:
- 6), APT3Histo4 (SEQ ID NO:
- 7), APT3Histo5 (SEQ ID NO:
- 8), APT3Histo9 (SEQ ID NO:
- 9), APT3Cooc7 (SEQ ID NO:
- 10), and combinations thereof.
Dependencies are inferred from the claim text.