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US 11,396,571 B2Granted
Polymers including galactose based blocks and uses thereof
AssigneeRegents of the University of Minnesota
InventorsTheresa M. Reineke, Yogesh Khemchandra Dhande, Bharat Sanjay Wagh
Life of this patent
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Abstract
Block copolymers that include one or more galactose based blocks and one or more cationic blocks; polyplexes including disclosed block copolymers and one or more nucleic acids; and methods of delivering a nucleic acid to a cell which can include delivering a polyplex to the cell.
Claims17
A block copolymer comprising:
- one or more N-acetyl-D-galactosamine (GNA) based blocks;
- and
- one or more cationic blocks.
A polyplex comprising:
- a block copolymer comprising:
- one or more N-acetyl-D-galactosamine (GNA) based blocks;
- and
- one or more cationic blocks;
- and
- one or more nucleic acids.
3 more elements
A method of delivering a nucleic acid to a cell, the method comprising:
- delivering a polyplex to a cell, the polyplex comprising:
- a block copolymer comprising:
- one or more N-acetyl-D-galactosamine (GNA) based blocks;
- and
- one or more cationic blocks;
- and
- one or more nucleic acids.
4 more elements
Dependencies are inferred from the claim text.