Back to results
US 11,391,738 B2Granted
Method of detecting cancer
AssigneeSienna Cancer Diagnostics Inc.
InventorsMinesh Lalla, Fabio Turatti, Sharyn Wilson
Life of this patent
Estimating the term…
Abstract
The disclosure provides methods for resolving an inconclusive cytological assessment of clinically relevant cells in a sample obtained from a patient based on the cytological detection of an antibody binding to a diagnostic protein in the clinically relevant cells in the sample.
Claims10
A method for detecting a cancer epithelial cell comprising:
- performing a cytological assessment of cells in a fluid biopsy sample comprising epithelial cells, wherein said performing detects epithelial cells having an atypical cell morphology that is indeterminate of malignancy,
- contacting the fluid biopsy sample with an anti-telomerase antibody;
- and
- detecting binding of the anti-telomerase antibody to the epithelial cells having atypical cell morphology that is indeterminate of malignancy,
- wherein the fluid biopsy sample is from thyroid or breast from a subject suspected of having cancer, and
- wherein the cancer epithelial cell is a thyroid cancer epithelial cell or a breast cancer epithelial cell.
3 more elements
Dependencies are inferred from the claim text.