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US 11,390,900 B2Granted
Antimicrobial cartridges and processes for multiplexed antimicrobial susceptibility testing
AssigneeSelux Diagnostics, Inc.
InventorsEric Stern, Kelly Flentie, Aleksandar Vacic, Frederick P. Floyd, Sarah A. Scott
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Abstract
The present invention provides, among other things, cartridges for multiplexed antimicrobial susceptibility testing (AST), single cartridges useful for both AST and quality control of AST, and systems and methods relating thereto.
Claims21
A cartridge for performing antimicrobial susceptibility testing of microorganisms, comprising:
- a plurality of reservoirs arranged in a series of rows and columns, each reservoir containing an antimicrobial agent;
- and
- a plurality of reservoir sets, each reservoir set comprising a series of adjacent reservoirs along a row of the cartridge and comprising a dilution series of the same antimicrobial agent;
- wherein the columns of reservoirs within the cartridge are divided into at least two regions, wherein each region comprises a group of columns for receiving a quality control organism that is different from a quality control organism received by a different region, and each region has at least two reservoir sets for assessing the antimicrobial susceptibility of the quality control organism received in that region;
- wherein the reservoir sets within each region comprise different antimicrobial agents from each other;
- and
- wherein the cassette is adapted to receive a patient sample or first and second quality control organisms, the first quality control organism being applied to a reservoir set within a first region of the at least two regions, and the second quality control organism being applied to a reservoir within a second region of the at least two regions.
4 more elements
Dependencies are inferred from the claim text.