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US 11,389,548 B2Granted
Oral food challenge meal formulations
AssigneeReacta Biotech Limited
InventorsClare Mills, Anuradha Balasundaram, Carol Ann Costello, Ivona Baricevic-Jones
Life of this patent
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Abstract
This invention relates to kits including novel oral food challenge meal formulations. In particular, the invention also relates to kits including novel oral food challenge meal formulations, wherein the placebo dose formulation is indistinguishable from non-placebo dose formulations.
Claims12
A kit comprising:
- a placebo challenge meal dessert formulation comprising no food allergen;
- and
- a non-placebo challenge meal dessert formulation comprising food allergen of between about 0.5% w/w to about 10% w/w, based on the total weight of the non-placebo challenge meal dessert formulation, wherein the allergen component in the non-placebo challenge meal dessert formulation is selected from the group consisting of:
- peanut, soy, egg, sesame seeds, milk, fish, crustaceans, almond, cashew, hazelnut, pistachio, walnut, sulphites, wheat, mustard and celery allergen;
- wherein the placebo and the non-placebo challenge meal dessert formulations each comprise:
- 20% w/w to 60% w/w of a matrix formation component, wherein the matrix formation component comprises a starch and sucrose,
- 10% w/w to 35% w/w of a texturizing component, wherein the texturizing component comprises an oil and a surfactant,
- 10% w/w to 45% w/w of a flavor/color masking component, and
- an additive present in an amount of from about 0.05% w/w to about 1.0% w/w, based on the total weight of each of the placebo and the non-placebo challenge meal dessert formulations, wherein the additive is selected from the group consisting of:
- maltodextrin, dextrin, and combinations thereof, and
- wherein, upon reconstitution with water, the placebo and the non-placebo challenge meal dessert formulations each form a mousse.
8 more elements
Dependencies are inferred from the claim text.