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US 11,389,461 B2Granted
Spironolactone aqueous compositions
AssigneeCmp Development LLC
InventorsAnthony Pipho, Michael Paul DeHart
Life of this patent
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Abstract
Disclosed herein is a stable, ready-to-use liquid formulation comprising spironolactone and its method of use.
Claims30
A ready-to-use liquid formulation, comprising:
- micronized spironolactone in an amount of about 5 mg/mL;
- xanthan gum in an amount to provide a formulation viscosity of from 100 cP to 300 cP,
- glycerin in an amount of from 18 mg/mL to 24 mg/mL;
- a sufficient amount of a citrate buffer to maintain a pH of the formulation from 4.5 to 5.5 and
- a water vehicle.
2 more elements
A ready-to-use liquid formulation, comprising:
- micronized spironolactone in an amount of about 5 mg/mL;
- xanthan gum in an amount to provide a formulation viscosity of from 100 cP to 300 cP,
- a dispersing agent consisting of glycerin in an amount of from 18 mg/mL to 24 mg/mL;
- a sufficient amount of a citrate buffer to maintain a pH of the formulation from 4.5 to 5.5 and
- a water vehicle.
2 more elements
Dependencies are inferred from the claim text.