EHV with inactivated UL18 and/or UL8
OwnerRamesh Koukuntla, Jana M. Larsen +3inventors
InventorsRamesh Koukuntla, Jana M. Larsen, Robert Barry Mandell, Luka N. Pelz, Eric Martin Vaughn
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Abstract
The present invention relates to the field of (vector) vaccines, and especially to novel EHV's having an inactivation of UL18 and/or UL8. The present invention further concerns related expression cassettes and vectors, which are suitable to express genes of interest, especially antigen encoding sequences. The viral vectors of the present invention are useful for producing an immunogenic composition or vaccine.
Claims19
A replication deficient Equid Alphaherpesvirus (EHV) vector comprising an inactivation of UL18 and/or UL8, wherein the inactivation of UL18 and/or UL8 is a complete or partial deletion, a complete or partial truncation, a complete or partial inversion, or an insertion.
Dependencies are inferred from the claim text.