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US 11,384,056 B2Granted
Method for the manufacturing of delmopinol intermediates
AssigneeLundbeck Pharmaceuticals Italy S.P.A.
InventorsCarla De Faveri, Mariano Stivanello
Life of this patent
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Abstract
The present invention relates to a new process for producing intermediates useful in the manufacture of 2-(3-(4-propylheptyl)morpholino)ethan-1-ol. The invention also relates to intermediates 1-chloro-4-propylhept-3-ene and 1-iodo-4-propyl-hept-3-ene.
Claims19
A process for manufacturing of delmopinol, which process comprises the use of 1-halo-4-propylhept-3-ene,
- wherein said 1-halo-4-propylhept-3-ene (IV) is converted to 1-halo-4-propylheptane (V) by catalytic hydrogenation
- wherein the catalytic hydrogenation takes place in an alcohol or an organic acid.
Dependencies are inferred from the claim text.