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US 11,380,534 B2Granted
Sample analysis systems and methods of use thereof
AssigneePurdue Research Foundation
InventorsRobert Graham Cooks, Zane Baird, Pu Wei
Life of this patent
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Abstract
The invention generally relates to sample analysis systems and methods of use thereof. In certain aspects, the invention provides a system for analyzing a sample that includes an ion generator configured to generate ions from a sample. The system additionally includes an ion separator configured to separate at or above atmospheric pressure the ions received from the ion generator without use of laminar flowing gas, and a detector that receives and detects the separated ions.
Claims16
A system for manipulating a sample, the system comprising:
- an ion generator configured to generate ions from a sample;
- an ion separator configured to separate at or above atmospheric pressure the ions received
- from the ion generator without use of laminar flowing gas, wherein the ion separator comprises a chamber and a plurality of electrodes physically coupled to each other, arranged sequential to each other, and that are configured such that upon application of voltage to the electrodes, ions received from the ion injector are separated as they travel through the chamber, wherein none of the plurality of electrodes are parallel to each other;
- an electrical element that selectively prevents transmission of the generated ions into the ion separator until a threshold voltage is exceeded, wherein the electrical element comprises a plurality of wire meshes that are separated from each other and configured such that a second of the plurality of meshes is held flush to an opening of the ion separator;
- and
- an ion focusing element that focuses the separated ions from the ion separator at or above atmospheric pressure.
3 more elements
A method for manipulating sample ions, the method comprising:
- generating ions from a sample at or above atmospheric pressure;
- separating the ions at or above atmospheric pressure without use of laminar flowing gas, wherein separating comprises sending the ions into a chamber that comprises a plurality of electrodes physically coupled to each other, arranged sequential to each other, and that are configured such that upon application of voltage to the electrodes, the ions received from the ion injector are separated as they travel through the chamber, wherein none of the plurality of electrodes are parallel to each other;
- an electrical element that selectively prevents transmission of the generated ions into the ion separator until a threshold voltage is exceeded, wherein the electrical element comprises a plurality of wire meshes that are separated from each other and configured such that a second of the plurality of wire meshes is held flush to an opening of the ion separator;
- and
- focusing the separated ions at or above atmospheric pressure, thereby manipulating the sample ions.
2 more elements
Dependencies are inferred from the claim text.