Computational localization of fibrillation sources

A computing system for generating a library of computational models for identifying a source location of an abnormal pattern within an organ of a target patient, the computing system comprising:

• one or more processors;
• and
• one or more memories storing instructions, which when executed by the one or more processors, cause operations comprising, for each of a plurality of sets of characteristics of the organ:
• running a simulation to generate a computational model of the organ based on that set of characteristics of the organ, the characteristics including the source location of an abnormal pattern;
• generating a representation of electrical activations of the organ using that computational model of the organ;
• and
• storing in the library that representation of the electrical activations of the organ and an indication of the source location of the set of characteristics
• wherein the sets of characteristics are not derived from the target patient.

A computing system for identifying a possible source location of an arrhythmia within a heart of a target patient, the computing system comprising:

• one or more processors;
• and
• one or more memories storing instructions, which when executed by the one or more processors, cause operations comprising:
• accessing a library that includes cardiograms associated with source locations of arrhythmias within a heart wherein the cardiograms are generated based on simulations of electrical activations of hearts based on characteristics of the hearts that are not specific to the heart of the target patient, the characteristics of the hearts including a source location of an arrhythmia;
• receiving a cardiogram of the target patient;
• searching the library for one or more cardiograms that match the cardiogram of the target patient;
• and
• designating as a possible source location for the target patient a source location associated with a matching cardiogram.

A method performed by one or more computing systems for identifying a possible location of an abnormal pattern within an organ of a target patient, the method comprising:

• accessing a library that includes representations of electrical activations of the organ, the representations generated based on simulations of electrical activations of the organ and based on locations of abnormal patterns within the organ, the representations not including a representation generated based on the organ of the target patient;
• receiving a representation of electrical activations of the organ of the target patient;
• searching the library for one or more representations of electrical activations that match the representation of the electrical activations of the target patient;
• and
• designating as the possible location of an abnormal pattern for the target patient the location associated with a matching representation of electrical activations.