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US 11,377,687 B2Granted
Methods of genomic evaluation in livestock
AssigneeInguran, LLC
InventorsJuan F. Moreno, John Dobrinsky, David Kendall, Claas Heuer
Life of this patent
Estimating the term…
Abstract
The invention encompasses methods for increasing genetic progress in livestock, and for genetic dissemination, including the use of amniocentesis to obtain fetal amniocytes for use in genomic evaluation and cloning.
Claims23
A method of determining a genomic estimated breeding value (GEBV) or a genomic predicted transmitting ability (GPTA) of a non-human mammalian fetus or embryo comprising:
- removing a tissue or a cell sample directly from an embryo or fetus while the fetus or embryo is gestating in a female, the fetus or embryo remaining viable in the female after the tissue or cell sample is removed;
- extracting DNA from one or more fetal or embryonic cells derived from the tissue or cell sample;
- genotyping the DNA to obtain a genotype for the fetus or embryo;
- determining a GEBV or a GPTA of the fetus or embryo based on the genotype;
- selecting the fetus or embryo as a parent based on the genotype;
- and
- producing offspring developed from the fetus or embryo.
4 more elements
A method of increasing genetic progress in a population of non-human mammals comprising:
- removing a tissue or a cell sample directly from an embryo or fetus while the fetus or embryo is gestating in a female, the fetus or embryo remaining viable in the female after the tissue or cell sample is removed;
- extracting DNA from one or more fetal or embryonic cells derived from the tissue or cell sample;
- genotyping the DNA to obtain a genotype for the fetus or embryo;
- selecting the fetus or embryo as a parent for the population based on the genotype;
- and
- producing offspring developed from the fetus or embryo.
3 more elements
A method of genetic dissemination comprising:
- removing a tissue or a cell sample directly from an embryo or fetus while the fetus or embryo is gestating in a female, the fetus or embryo remaining viable in the female after the tissue or cell sample is removed;
- extracting DNA from one or more fetal or embryonic cells derived from the tissue or cell sample;
- genotyping the DNA to obtain a genotype for the fetus or embryo;
- selecting the fetus or embryo as a donor of oocytes for use in IVF based on the genotype;
- and
- producing offspring developed from the fetus or embryo.
3 more elements
Dependencies are inferred from the claim text.