Metal nanocluster scaffolds
AssigneeAsociacióN Centro De InvestigacióN Cooperativa En Biomateriales—Cic Biomagune
InventorsAitziber López Cortajarena, Antonio Aires Trapote
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Abstract
The present invention refers to a protein-stabilized metal nanocluster comprising a variant of the helix A of the CTPR. It is also related to its uses for delivering of a drug, for interfering a metabolic reaction, for catalyzing a chemical reaction, as biocatalyst, for detecting an analyte, for phasing crystallographic data set, for cell labeling, for specific protein labeling, as biosensor, as a temperature sensor, as photosensitizer, or for the manufacture of an optoelectronic device.
Claims19
A peptide consisting of an amino acid sequence set forth in SEQ ID NO:
- 1 or a salt thereof:
- (SEQ ID NO:
- 1)
- AX1AWX2X3LGX4AYX5X6
- wherein
- X1 is an amino acid selected from E, H, C, and D;
- X2 is an amino acid selected from Y, H, C, D and E;
- X3 is an amino acid selected from N, H, C, D and E;
- X4 is an amino acid selected from N, H, C, D and E;
- X5 is an amino acid selected from Y, H, L, A, V, C, D and E;
- X6 is an amino acid selected from K, H, C, D and E;
- provided that at least two of X1, X2, X3, X4, X5 and X6 are the same or different and represent H, C, D or E.
Dependencies are inferred from the claim text.