Triazoles for regulating intracellular calcium homeostasis

A compound of formula (I):

• where
• R1 is a C1-4 alkylene biradical optionally substituted with one or more substituents independently selected from the group consisting of C1-4 alkyl, C6-10 aryl, F, Cl, CN and NO2;
• R2 is a C1-4 alkylene biradical optionally substituted with one or two substituents independently selected from the group consisting of methyl, ethyl, propyl, isopropyl, allyl, propargyl, butyl, isobutyl, sec-butyl, tert-butyl, hydroxymethyl, 1-hydroxyethyl, 2-hydroxyethyl, 3-aminopropyl, 4-aminobutyl, 3-guanidylpropyl, 3-indolylmethyl, phenyl, 1-naphthyl, 2-naphthyl, benzyl, 4-hydroxybenzyl, C6-10 heteroaryl;
• R3 is H;
• m is selected from 0, 1, 2 and 4;
• n is selected from 0, 1 and 2;
• X is independently selected from the group consisting of OH, O(C1-4 alkyl), O(C6-10 aryl), OCF3, S(C1-4 alkyl), S(C6-10 aryl), C1-6 alkyl, CF3, NHC(O)(C1-4 alkyl) and halogen;
• or two X groups can represent a methylenedioxy, ethylenedioxy or propylenedioxy biradical;
• and
• Y is selected from the group consisting of —CO2H, —CO2(C1-4 alkyl), —N(C1-4 alkyl)2, or a pharmaceutically acceptable stereoisomer, salt, solvate or complex thereof, or an isotopically labeled derivative.