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US 11,376,432 B2Granted
Non-invasive periocular device for dry-eye treatment
AssigneeTwenty Twenty Therapeutics LLC
InventorChristian Gutierrez
Life of this patent
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Abstract
A periocular ring configured to be worn on an eye of a user that includes a plurality of electrodes spaced along the periocular ring; a microcontroller; and a lead assembly extending along at least a portion of the periocular ring; wherein the lead assembly extends between the microcontroller and the plurality of electrodes to operably couple the plurality of electrodes to the microcontroller; and wherein the microcontroller is configured to activate the plurality of electrodes via the lead assembly to stimulate a lacrimal gland of the user. The periocular ring has an opening that defines an innermost diameter; and wherein, when the periocular ring is worn on the eye of the user, a portion of the eye extends through the opening of the periocular ring.
Claims17
A periocular ring configured to be worn on an eye of a user comprising:
- the periocular ring having an opening;
- wherein, when the periocular ring is worn on the eye of the user, a portion of the eye extends through the opening of the periocular ring;
- a plurality of stimulating electrodes spaced along the periocular ring, wherein the plurality of stimulating electrodes includes a pair of stimulating electrodes configured to stimulate a lacrimal gland of the user;
- a plurality of sensors spaced along the periocular ring;
- and
- a microcontroller operably coupled to the plurality of stimulating electrodes and the plurality of sensors;
- wherein the microcontroller is configured to activate the plurality of stimulating electrodes to stimulate a lacrimal gland of the user;
- wherein at least one of the plurality of stimulating electrodes is located at a first radial location of the periocular ring and extends over a first portion of a cross-sectional circumference of the periocular ring at the first radial location, and
- wherein at least one of the plurality of sensors is located at a second radial location of the periocular ring and extends over a second portion of the cross-sectional circumference of the periocular ring at the second radial location, wherein the second portion of the cross-sectional circumference of the periocular ring is different from the first portion of the cross-sectional circumference of the periocular ring.
6 more elements
A periocular assembly configured to be worn on an eye of a user and circumscribe an iris of the user, the periocular assembly comprising:
- a periocular ring;
- a plurality of stimulating electrodes spaced along the periocular assembly, wherein the plurality of stimulating electrodes includes a pair of stimulating electrodes configured to stimulate a lacrimal gland of the user;
- a plurality of sensors spaced along the periocular assembly;
- a first microcontroller comprising a memory;
- wherein a temporal model associated with the user is stored in the memory;
- and
- a lead assembly extending along at least a portion of the periocular assembly;
- wherein the lead assembly extends between the first microcontroller and the plurality of stimulating electrodes to operably couple the plurality of stimulating electrodes to the first microcontroller;
- wherein the periocular assembly is configured to be positioned in the eye of the user so that the at least one electrode of the pair of stimulating electrodes is positioned proximate to the lacrimal gland and the first microcontroller is positioned between a lower lid of the user and the eye;
- and
- wherein the first microcontroller is configured to activate the plurality of stimulating electrodes to stimulate the lacrimal gland of the user based on the temporal model associated with the user;
- wherein at least one of the plurality of stimulating electrodes is located at a first radial location of the periocular assembly and extends over a first portion of a cross-sectional circumference of the periocular assembly at the first radial location, and
- wherein at least one of the plurality of sensors is located at a second radial location of the periocular assembly and extends over a second portion of the cross-sectional circumference of the periocular assembly at the second radial location, wherein the second portion of the cross-sectional circumference of the periocular assembly is different from the first portion of the cross-sectional circumference of the periocular assembly.
10 more elements
A method of stimulating a lacrimal gland of a user using a periocular device that is positioned between an eyelid and an eye of the user;
- wherein the periocular device comprises:
- a ring configured to be worn on the eye of the user;
- a plurality of sensors spaced along the periocular device;
- and
- a stimulator assembly comprising:
- a plurality of stimulating electrodes spaced along the ring, wherein the plurality of stimulating electrodes includes a pair of stimulating electrodes configured to stimulate the lacrimal gland;
- and
- a microcontroller operably coupled to the plurality of stimulating electrodes and comprising a memory;
- wherein stimulation parameters are stored in the memory;
- wherein the periocular device is positioned in an upper and lower fornix of the eye of the user so that the at least one electrode of the pair of stimulating electrodes is positioned proximate to the lacrimal gland;
- and
- wherein at least one of the plurality of stimulating electrodes is located at a first radial location of the periocular device and extends over a first portion of a cross-sectional circumference of the periocular device at the first radial location, and
- wherein at least one of the plurality of sensors is located at a second radial location of the periocular device and extends over a second portion of the cross-sectional circumference of the periocular device at the second radial location, wherein the second portion of the cross-sectional circumference of the periocular device is different from the first portion of the cross-sectional circumference of the periocular device;
- and
- wherein the method comprises activating, using the microcontroller and based on the stimulation parameters, the plurality of stimulating electrodes to stimulate the lacrimal gland of the user.
12 more elements
Dependencies are inferred from the claim text.