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US 11,376,302 B2Granted
Methods for treating depression and major depressive disorder
AssigneeCarmel-Haifa University Economic Corp. Ltd.
InventorsYaacov Rozenblum, Elham Taha, Chinnakkaruppan Adaikkan
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Abstract
Methods for treating depression in, and decreasing a dose of ketamine given to, a subject in need thereof, comprising, administering a CaMKII inhibitor are provided.
Claims15
A method for treating or ameliorating a depression, in a subject in need thereof, the method comprising administering to said subject a calcium/calmodulin-dependent protein kinase II (CaMKII) inhibitor, thereby treating depression, wherein said CaMKII inhibitor is TatCN21;
- wherein the method further comprising administering to said subject a CaMKII activator at least 30 minutes after administering said inhibitor.
Dependencies are inferred from the claim text.