Synergistic medicinal compositions for treating dysfunctional D-serine signaling
AssigneeCelagenex Research (India) Pvt. Ltd.
InventorsRajaram Samant, Rajendra Prasad Tongra
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Abstract
The invention disclosed herein relates to novel synergistic medicinal compositions for treating dysfunctional D-serine (DSR) signaling. Particularly the invention provides potent synergistic medicinal composition comprising combination of N-acetyl taurinate salt of divalent metal (M2+AT) as serine racemase enzyme (SR) activator/stimulator and benzoic acid ester salt of monovalent or divalent metals (M+/2+Bz) as d-amino acid oxidase enzyme (DAAO) inhibitor, which are present in weight ratio of 1:0.001 to 1:1.5 along with pharmaceutically acceptable excipients. Further the present synergistic medicinal composition is useful for treating certain neuropsychiatric disorders, neurological disorders and metabolic disorders.
Claims5
A synergistic medicinal composition, comprising:
- therapeutically active, medicinal ingredients and pharmaceutically acceptable excipients, wherein the therapeutically active, medicinal ingredients consisting of magnesium acetyl taurate and sodium benzoate in a weight ratio of 1:0.001 to 1:1.5, wherein the composition is effective for treating dysfunctional D-serine signaling.
Dependencies are inferred from the claim text.