Methods of treating bacterial infections
AssigneeMelinta Subsidiary Corp.
InventorsElizabeth Alexander, Jeffrey S. Loutit, Michael N. Dudley
Life of this patent
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Abstract
Methods of treating bacterial infection in immunocompromised subjects and subjects with one or more underlying malignancies include administering a combination of meropenem and vaborbactam to the subject. Suitable subjects to be treated can include a subject with a history of ongoing leukemia or lymphoma, a subject that has had an organ transplant, stem cell transplant, bone marrow transplant, or splenectomy, a subject receiving immunosuppressive medications, a subject receiving bone marrow ablative chemotherapy, a subject with neutropenia and subject suffering from or having suffered from a malignancy.
Claims20
A method of treating one or more bacterial infection in a subject, wherein the subject is immunocompromised, comprising administering to the subject in need thereof a combination of meropenem and vaborbactam.
A method of treating one or more bacterial infection in a subject, wherein the subject is suffering from or has suffered from a malignancy, comprising administering to the subject in need thereof a combination of meropenem and vaborbactam.
Dependencies are inferred from the claim text.