Composition, containing sarpogrelate as active ingredient, for preventing or treating sensorineural hearing loss
AssigneeAjou University Industry-Academic Cooperation Foundation
InventorsYun-Hoon Choung, Young Sun Kim, Young-Joon Park
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Abstract
The present invention relates to a pharmaceutical composition, containing sarpogrelate or a pharmaceutically acceptable salt thereof as an active ingredient, for preventing, alleviating, or treating sensorineural hearing loss. The sarporgrelate according to the present invention protects against hearing loss caused by noise through the suppression of auditory cell apoptosis and the expression increase of antioxidant enzyme in auditory cells, and thus can be advantageously used in the prevention and alleviation of sensorineural hearing loss.
Claims10
A method of preventing or treating sensorineural hearing loss, the method comprising:
- administering sarpogrelate or a pharmaceutically acceptable salt thereof.
A method of preventing or treating sensorineural hearing loss, the method comprising:
- administering a complex preparation containing sarpogrelate or a pharmaceutically acceptable salt thereof, and at least one selected from the group consisting of a Korean red ginseng extract, a Ginkgo biloba extract, resveratrol, and a European Vitis vinifera dry leaf extract.
A method of preventing or treating sensorineural hearing loss, the method comprising:
- co-administering sarpogrelate or a pharmaceutically acceptable salt thereof with at least one selected from the group consisting of a Korean red ginseng extract, a Ginkgo biloba extract, resveratrol, and a European Vitis vinifera dry leaf extract.
Dependencies are inferred from the claim text.