Devices, systems, and methods for treatment of vascular defects

A vascular occlusion device for treating an aneurysm, wherein a neck of the aneurysm opens to a blood vessel, the device comprising:

• an expandable mesh having an elongated configuration and a deployed configuration, wherein, in the deployed configuration, the mesh includes:
• a proximal portion formed of a braid configured to contact and conform to an inner surface of the aneurysm,
• a distal portion,
• an intermediate mesh portion extending between the proximal portion and the distal portion, wherein the intermediate mesh portion is curved such that the distal portion is positioned at a predetermined angle with respect to the proximal portion;
• and
• a directing region at the distal portion of the expandable mesh having a proximal terminus and a distal terminus, wherein the directing region extends from the proximal terminus to the distal terminus, and wherein the directing region is positioned at an angle relative to the proximal portion between about 45 degrees and about 135 degrees, and
• wherein, when the device is being pushed distally out of a delivery catheter into the aneurysm, the directing region directs the distal portion to inhibit the distal portion from exiting the aneurysm through the neck such that the proximal portion crosses the neck and generally remains within the aneurysm,
• wherein the device is configured to be implanted within the aneurysm.