Drug patterned reinforcement material for circular anastomosis

A staple cartridge assembly comprising:

• a staple cartridge including a tissue facing surface having staple retaining slots defined therein, each staple retaining slot housing a staple therein, and a circular knife disposed radially inwardly of the tissue facing surface;
• and
• a surgical buttress releasably coupled to the staple cartridge, the surgical buttress having a circular configuration including an inner edge defining a central aperture therethrough and an outer edge, the surgical buttress having a plurality of concentric regions including a first concentric region, a second concentric region extending around the first concentric region, and a third concentric region extending around the second concentric region, and a therapeutic coating disposed on at least a portion of the first or second concentric regions, the third concentric region free of the therapeutic coating.

An anvil assembly comprising:

• an anvil assembly including an anvil member including a tissue facing surface and an anvil shaft extending from the anvil member;
• and
• a surgical buttress releasably coupled to the anvil assembly, the surgical buttress having a circular configuration including an inner edge defining a central aperture therethrough and an outer edge, the surgical buttress having a plurality of concentric regions including a first concentric region, a second concentric region extending around the first concentric region, and a third concentric region extending around the second concentric region, and a therapeutic coating disposed on at least a portion of the first or second concentric regions, the third concentric region free of the therapeutic coating.