Tissue-engineered electronic peripheral nerve interface
AssigneeUniversity of Florida Research Foundation, Inc.
InventorsJack Judy, Christine E. Schmidt, Kevin Otto, Carlos Rinaldi, Cary A. Kuliasha
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Abstract
Tissue-engineered electronic peripheral nerve interface (TEENI) devices, methods of using TEENI devices, and systems using TEENI devices are provided. In particular, TEENI devices include a support member having a length, at least one thread set comprising a plurality thread set arms having a plurality of electronic leads running through the thread set arms and being fully encapsulated within the support member, and a plurality of electrodes fixed to the plurality of thread set arms.
Claims15
A tissue-engineered electronic peripheral nerve interface (TEENI) device comprising:
- a biomaterial support member having a length;
- at least one thread set comprising a plurality of thread set arms having a plurality of electronic leads running through the thread set arms, the thread set arms being fully encapsulated within the biomaterial support member;
- and
- a plurality of electrodes fixed to the thread set arms,
- wherein when the TEENI device is sutured into a subject in need thereof, the plurality of thread set arms are configured to be positioned at least partially within a transected nerve.
A system for supporting a transected nerve, the system comprising:
- a tissue-engineered electronic peripheral nerve interface (TEENT) device, the TEENI device comprising:
- a biomaterial support member;
- a thread set comprising a plurality of thread set arms having a plurality of electronic leads running through the thread set arms, the thread set arms being fully encapsulated within the biomaterial support member;
- and
- a plurality of electrodes fixed to the plurality of thread set arms,
- wherein when the TEENI device is sutured into a subject in need thereof, the plurality of thread set arms are configured to be positioned at least partially within the transected nerve:
- a control element comprising processing circuitry configured to:
- detect neural activity as a signal in a regenerated nerve,
- amplify the signal,
- record the neural activity in the regenerated nerve, and
- stimulate the regenerated nerve;
- a connecting element comprising a plurality of suture holes and a plurality of connecting element electronic leads connected to the TEENI device and extending to the control element;
- and
- a downstream element configured to communicate with the transected nerve via the control element.
Dependencies are inferred from the claim text.