Substrate, structure, structure-manufacturing method, cell-sorting method, cell-manufacturing method, and secretion-producing method

A structure comprising:

• a first substrate;
• and
• a second substrate disposed to face one side of the first substrate,
• wherein the first substrate has a plurality of depressions which are open to the other side of the first substrate and each of which has a size that enables each of the depressions to capture one unit of a cell,
• at least some of the depressions have only 2 to 4 communication holes per one depression, the communication holes communicating with one side and the other side of the first substrate and each of which has a size that enables secretions secreted from the cell to move through each of the communication holes,
• the second substrate includes a supporting member which supports the first substrate, and accumulation portions in which the secretions moving through the communication holes are accumulated,
• the one side of the second substrate that faces first substrate has a generally flat major surface,
• the accumulation portions are formed in a space defined by the second substrate and the supporting member, and the accumulation portions include a fixed layer containing a substance having an affinity with the secretions secreted from one unit of the cell, and corresponds to the depressions,
• the first substrate and the second substrate are made of a transparent material, and
• the first substrate is made of a polymer of a curable resin composition.