K-Ras modulators

A compound having formula (II):

• or a pharmaceutically acceptable salt thereof, wherein:
• Ring A is phenyl, indolinyl, indazolyl, benzimidazolyl, benzoxazolyl, azaindolyl, purinyl, indolyl, pyrazinyl, pyrrolyl, imidazolyl, pyrazolyl, triazolyl, tetrazolyl, benzofuranyl, benzothienyl,
• R1 is independently halogen, —CX13, —CHX12, —CH2X1, —CN, —SOn1R1D, —SOv1NR1AR1B, —NHNR1AR1B, —ONR1AR1B, —NHC=(O)NHNR1AR1B, —NHC(O)NR1AR1B, —N(O)m1, —NR1AR1B, —C(O)R1C, —C(O)—OR1C, —C(O)NR1AR1B, —OR1D, —NR1ASO2R1D, —NR1AC(O)R1C, —NR1AC(O)OR1C, —NR1AOR1C, —OCX13, —OCHX12, —OCH2X1, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, or substituted or unsubstituted heterocycloalkyl;
• or two adjacent R1 substituents may optionally be joined to form a substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• z1 is an integer from 0 to 4;
• L2 is —S(O)2—, —C(O)NH—, or —C(O)NHCH2—;
• L3 is a bond, —S(O)2—, —N(R3)—, —O—, —S—, —C(O)—, —C(O)N(R3)—, —N(R3)C(O)—, —N(R3)C(O)NH—, —NHC(O)N(R3)—, —C(O)O—, —OC(O)—, unsubstituted alkylene, unsubstituted heteroalkylene, substituted or unsubstituted cycloalkylene, substituted or unsubstituted arylene, or unsubstituted heteroarylene;
• R3 is independently hydrogen, —CX33, —CHX32, —CH2X3, —C(O)R3A, —C(O)OR3A, —C(O)NR3AR3B, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• L4 is a bond, —S(O)2—, —N(R4)—, —O—, —S—, —C(O)—, —C(O)N(R4)—, —N(R4)C(O)—, —N(R4)C(O)NH—, —NHC(O)N(R4)—, —C(O)O—, —OC(O)—, substituted or unsubstituted alkylene, unsubstituted heteroalkylene, substituted or unsubstituted cycloalkylene, or substituted or unsubstituted heterocycloalkylene;
• R4 is independently hydrogen, —CX43, —CHX42, —CH2X4, —C(O)R4A, —C(O)OR4A, —C(O)NR4AR4B, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• R5 is independently:
• wherein R13 is hydrogen, halogen, substituted or unsubstituted alkyl;
• and z13 is an integer from 0 to 3;
• each R1A, R1B, R1C, R1D, R3A, R3B, R4A, and R4B is independently hydrogen, —CX3, —CN, —COOH, —CONH2, —CHX2, —CH2X, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• R1A and R1B substituents bonded to the same nitrogen atom may optionally be joined to form a substituted or unsubstituted heterocycloalkyl or substituted or unsubstituted heteroaryl;
• R3A and R3B substituents bonded to the same nitrogen atom may optionally be joined to form a substituted or unsubstituted heterocycloalkyl or substituted or unsubstituted heteroaryl;
• R4A and R4B substituents bonded to the same nitrogen atom may optionally be joined to form a substituted or unsubstituted heterocycloalkyl or substituted or unsubstituted heteroaryl;
• each X, X1, X3, and X4 is independently —F, —Cl, —Br, or —I;
• n1 is independently an integer from 0 to 4;
• and
• m1 and v1 are independently 1 or 2.