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US 11,344,623 B2Granted
Cholecystokinin B receptor targeting for imaging and therapy
AssigneePurdue Research Foundation
InventorsPhilip Stewart Low, Charity Wayua
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Abstract
Conjugates are described herein where CCK2R targeting ligands are attached to an active moiety, such as therapeutic agent or an imaging agent, through a linker. The conjugates can be used in the detection, diagnosis, imaging and treatment of cancer.
Claims14
A conjugate of the formula:
- B-L-D
- wherein
- B is a targeting ligand of Formula I
- L is a bivalent or polyvalent linker;
- and
- D is a fluorescein or fluorescein isothiocyanate (FITC) optical imaging agent;
- or a pharmaceutically acceptable salt thereof.
4 more elements
Dependencies are inferred from the claim text.