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US 11,338,054 B2Granted
Phosphocalcic cement composition comprising blood
AssigneesCentre National De La Recherche Scientifique, Universite De Nantes, Oniris, Graftys
InventorsJean-Michel Bouler, Olivier Gauthier, Bruno Bujoli, Pascal Janvier, Charlotte Mellier
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Abstract
A method for promoting spine fusion inside intersomatic cages, comprising placing a fusion cage between two vertebral bodies, and injecting a bone cement paste inside said fusion cage, said bone cement paste containing a powder component comprising α-tricalcium phosphate (α-TCP) particles having an average size greater than or equal to 9 μm, and a liquid component comprising blood.
Claims10
A method for promoting spine fusion inside intersomatic cages, comprising the following steps:
- placing a fusion cage between two vertebral bodies, and
- injecting a bone cement paste inside said fusion cage, said bone cement paste comprising a powder component and a liquid component comprising blood;
- wherein the powder component comprises in relation to the total weight of said powder component:
- from 70% to 80% by weight of α-tricalcium phosphate (α-TCP) particles having an average size greater than or equal to 9 μm, wherein said average size is the mean equivalent diameter of said particles measured by LASER diffraction analysis,
- from 1% to 10% by weight of monocalcium phosphate monohydrate (MCPM),
- from 1% to 10% by weight of dicalcium phosphate dihydrate (DCPD),
- from 5% to 15% by weight of calcium-deficient apatite (CDA), and
- from 0.1% to 5% by weight of a cellulose ester;
- and
- wherein the liquid component (L)/powder component (P) ratio is between 0.3 and 0.7 mL/g;
- and
- wherein the bone cement paste has a setting time ranging from 10 minutes to 72 hours.
9 more elements
Dependencies are inferred from the claim text.