Starch-derived clathrate-forming compositions
OwnerGary B. Nickelinventor
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Abstract
Embodiments of the present disclosure relate to materials and methods for preparing a clathrate-forming composition comprising a plurality of linear glucomonomer chains of about 15 to about 100 D-glucopyranosyl residues linked by α-1,4 linkages, wherein the linear glucomonomer chains are a product of partial amylolysis of a modified starch substrate and wherein the product is flowable at temperatures within a range of 4-20° C. at about 20% w/v solids content. The present disclosure further describes methods of using the clathrate-forming compositions to form molecular dispersions or clathrates with hydrophobic guest molecules, kits for use in these methods, and molecular dispersions or clathrates obtained from the materials.
Claims10
A clathrate-forming composition comprising a plurality of linear glucomonomer chains of about 15 to about 100 D-glucopyranosyl residues linked by α-1,4 linkages, wherein the linear glucomonomer chains are a product of partial amylolysis of a modified starch substrate, wherein the partially amylolyzed product is flowable at temperatures within a range of 4-20° C. at about 20% w/v solids content, wherein at least one of the glucomonomer chains is esterified.
A kit for forming a clathrate with a hydrophobic guest molecule comprising:
- a first container comprising a clathrate-forming composition comprising a plurality of linear glucomonomer chains of about 15 to about 100 D-glucopyranosyl residues linked by α-1,4 linkages, wherein the linear glucomonomer chains are a product of partial amylolysis of a modified starch substrate and wherein the product is flowable at temperatures within a range of 4-20° C. at about 20% w/v solids content;
- a second container comprising a hydrophobic guest molecule;
- instructions for preparing the clathrate;
- a third container comprising a plurality of amylose chains having a degree of polymerization of at least 250;
- and instructions for wrapping the clathrate in the amylose chains.
A kit for forming a clathrate with a hydrophobic guest molecule comprising:
- a first container comprising a clathrate-forming composition comprising a plurality of linear glucomonomer chains of about 15 to about 100 D-glucopyranosyl residues linked by α-1,4 linkages, wherein the linear glucomonomer chains are a product of partial amylolysis of a modified starch substrate and wherein the product is flowable at temperatures within a range of 4-20° C. at about 20% w/v solids content;
- instructions for preparing the clathrate with a hydrophobic guest molecule;
- a second container comprising a plurality of amylose chains having a degree of polymerization of at least 250;
- and
- instructions for wrapping the clathrate in the amylose chains.
Dependencies are inferred from the claim text.