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US 11,324,769 B2Granted
Polymorphic compounds and uses thereof
AssigneeAstrocyte Pharmaceuticals, Inc.
InventorsRussell Birch Poe, David T. Jonaitis, Lisa Michelle Grove
Life of this patent
Estimating the term…
Abstract
The present invention provides compounds and methods of use thereof for treatment of certain disorders and conditions, for example brain injuries such as stroke or traumatic brain injuries.
Claims40
A solid form of Compound A:
- wherein said solid form has 2 or more peaks in its XRPD pattern selected from the following °2θ (degrees 2-theta) values:
- 7.6, 8.0, 9.0, 10.8, 11.8, 12.5, 13.1, 16.2, 16.7, 17.2, 17.9, 18.1, 18.3, 19.8, 21.0, 21.5, 22.8, 23.1, 23.7, 23.9, 24.9, 26.1, 26.5, 26.6, 27.1, 28.6, 29.3, 29.7, 30.1, 30.4, 30.8, 32.0, 32.8, 32.9, 33.7, 34.7, 36.3, 36.7, 37.9, 38.2, 38.5, 38.7, and 39.6;
- wherein each °2θ value is within ±0.2 of the stated value.
A solid form of Compound A:
- wherein said solid form exhibits a DSC trace substantially as shown in FIG. 2.
A solid form of Compound A:
- wherein said solid form has 2 or more peaks in its XRPD pattern selected from the following °2θ (degrees 2-theta) values:
- 4.7, 7.6, 9.5, 10.0, 10.5, 13.8, 14.2, 14.7, 15.2, 15.4, 16.2, 17.1, 17.9, 18.3, 19.0, 20.1, 21.0, 21.5, 23.0, 23.8, 24.3, 24.6, 25.4, 25.6, 25.9, 26.2, 26.6, 27.6, 28.8, 29.1, 29.5, 29.9, 30.2, 30.6, 31.6, 32.3, 32.7, 33.1, 33.6, 35.9, 37.0, 37.4, and 39.0;
- wherein each °2θ value is within ±0.2 of the stated value.
A solid form of Compound A:
- wherein said solid form exhibits a DSC trace substantially as shown in FIG. 11.
Dependencies are inferred from the claim text.