Preservative-free treprostinil devices
AssigneeSteadyMed Ltd.
InventorsJonathan Rigby, Peter Noymer, Robert Zwolinski
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Abstract
Embodiments include a system including a sealed prefilled drug-reservoir. The drug-reservoir may include a unit dosage of treprostinil in a sterile fluid composition. The composition may not include an antimicrobial preservative. The treprostinil may be present at a dosage of between 0.1 mg/mL and 25 mg/mL. In addition, the treprostinil may be treprostinil sodium Furthermore, the composition may include sodium chloride. The composition may also include a sodium ion from sodium chloride in a concentration from 3000 to 4500 ppm. The composition may not include metacresol.
Claims16
A system comprising a sealed prefilled drug-reservoir containing a unit dosage form of treprostinil in a sterile fluid composition, wherein:
- said composition does not comprise an antimicrobial preservative,
- said treprostinil is present at a dosage of between 0.1 mg/mL and 25 mg/mL,
- said treprostinil is treprostinil sodium,
- said composition comprises sodium chloride,
- the composition comprises a sodium ion from sodium chloride in a concentration from 3000 to 4500 ppm, and
- said composition does not comprise metacresol.
Dependencies are inferred from the claim text.