Immune-modulating agents and uses therefor
AssigneeUniversity of Technology, Sydney
InventorsSheila Donnelly, Mark William Robinson, John Pius Dalton, Joyce To
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Abstract
This invention discloses the use of Heminth Defense Molecules in methods and compositions for modulating immune responses including treating or preventing undesirable or deleterious immune responses.
Claims17
A method for suppressing a tumor necrosis factor- or interleukin-1β-mediated immune response in a subject, the method comprising administering to the subject an effective amount of an isolated proteinaceous molecule, or a composition comprising the isolated proteinaceous molecule, wherein the proteinaceous molecule comprises an amphipathic helix, and wherein the isolated proteinaceous molecule comprises the amino acid sequence set forth in SEQ ID NO:46.
Dependencies are inferred from the claim text.